Peripherin 2/PRPH2 Antibody

Images

 
Western Blot: Peripherin 2/PRPH2 Antibody [H00005961-B01P] - Analysis of PRPH2 expression in transfected 293T cell line by PRPH2 polyclonal antibody. Lane 1: PRPH2 transfected lysate(39.10 KDa). Lane 2: Non-transfected ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

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Peripherin 2/PRPH2 Antibody Summary

Description
Quality control test: Antibody reactive against mammalian transfected lysate.
Immunogen
PRPH2 (AAH74720.1, 1 a.a. - 346 a.a.) full-length human protein. MALLKVKFDQKKRVKLAQGLWLMNWFSVLAGIIIFSLGLFLKIGLRKRSDVMNNSESHFVPNSLIGMGVLSCVFNSLAGKICYDALDPAKYARWKPWLKPYLAICVLFNIILFLVALCCFLLRGSLENTLGQGLKNGMKYYRDTDTPGRCFMKKTIDMLQIEFKCCGNNGFRDWFEIQWISNRYLDFSSKEVKDRIKSNVDGRYLVDGVPFSCCNPSSPRPCIQYQITNNSAHYSYDHQTEELNLWVRGCRAALLSYYSSLMNSMGVVTLLIWLFEVTITIGLRYLQTSLDGVSNPEESESESEGWLLEKSVPETWKAFLESVKKLGKGNQVEAEGAGAGQAPEAG
Isotype
IgG
Clonality
Polyclonal
Host
Mouse
Gene
PRPH2
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
It has been used for WB.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein G purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Peripherin 2/PRPH2 Antibody

  • AOFMD
  • AVMD
  • CACD2
  • CACD2peripherin 2, homolog of mouse
  • DS
  • peripherin 2 (retinal degeneration, slow)
  • Peripherin 2
  • peripherin-2
  • PRPH2
  • PRPHperipherin, photoreceptor type
  • rd2
  • RDS
  • Retinal degeneration slow protein
  • retinal degeneration, slow
  • retinal peripherin
  • RP7
  • Tetraspanin-22
  • TSPAN22
  • tspan-22
  • TSPAN22retinal degeneration, slow (retinitis pigmentosa 7)

Background

The protein encoded by the PRPH2 gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This encoded protein is a cell surface glycoprotein found in the outer segment of both rod and cone photoreceptor cells. It may function as an adhesion molecule involved in stabilization and compaction of outer segment disks or in the maintenance of the curvature of the rim. This protein is essential for disk morphogenesis. Defects in this gene are associated with both central and peripheral retinal degenerations. Some of the various phenotypically different disorders are autosomal dominant retinitis pigmentosa, progressive macular degeneration, macular dystrophy and retinitis pigmentosa digenic. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PRPH2
Uniprot