Canine reactivity reported in scientific literature (PMID: 23451256).
Packaging, Storage & Formulations
Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified
Notes
DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.
Alternate Names for Palladin Antibody (1E6) [DyLight 488]
CGI151
CGI-151
FLJ22190
FLJ38193
KIAA0992FLJ39139
MYN
myoneurin
Palladin
palladin, cytoskeletal associated protein
PALLD
PNCA1
Sarcoma antigen NY-SAR-77
SIH002
SIH002FLJ61376
Background
Palladin is a cytoskeletal protein required for organization of normal actin cytoskeleton. It plays roles in establishing cell morphology, motility, cell adhesion and cell-extracellular matrix interactions in a variety of cell types. Palladin may function as a scaffolding molecule with the potential to impact both actin polymerization as well as the assembly of existing actin filaments into higher-order arrays. It binds to proteins that bind to either monomeric or filamentous actin. It localizes at sites where active actin remodeling takes place, such as lamellipodia and membrane ruffles. Palladin's different isoforms may have functional differences. It is also involved in the control of morphological and cytoskeletal changes associated with dendritic cell maturation.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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