p130Cas/BCAR1 [p Tyr165] Antibody - Azide and BSA Free

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Western Blot: p130Cas/BCAR1 [p Tyr165] Antibody [NBP3-05456] - Western blot analysis of extracts of PC-12 cells, using p130Cas/BCAR1 antibody (NBP3-05456) at 1:1000 dilution. PC-12 cell lysate were treated by CIP (20ul ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free
Datasheet
Reviews & Publications
Protocols & FAQs
Support & Research

p130Cas/BCAR1 [p Tyr165] Antibody - Azide and BSA Free Summary

Immunogen
A synthetic phosphorylated peptide around Y165 of human p130Cas/BCAR1 (NP_055382.2). DLYQV
Modification
p Tyr165
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
BCAR1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol
Preservative
0.01% Thimerosal
Purity
Affinity purified

Alternate Names for p130Cas/BCAR1 [p Tyr165] Antibody - Azide and BSA Free

  • BCAR1
  • breast cancer estrogen resistance 1
  • Cas scaffolding protein family member 1
  • CAS1
  • CASFLJ45059
  • CASS1
  • CASS1CRKASbreast cancer estrogen resistance protein 1
  • CRKAS
  • Crk-associated substrate p130Cas
  • CRK-associated substrate
  • FLJ12176
  • p130Cas

Background

BCAR1/p130CAS functions as a scaffolding protein for components of various kinase signaling pathways. It is involved in integrin signaling for cell motility as well as netrin signaling for the guidance of commissural axons. Overexpression of BCAR1/p130CAS has been shown to confer antiestrogen resistance in breast cancer cells. Alternate names for BCAR1/p130CAS include breast cancer anti-estrogen resistance protein 1, CRK-associated substrate, CAS scaffolding protein family member 1, CAS, and CRKAS.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov
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Bioinformatics

Gene Symbol BCAR1