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Optineurin Antibody [HRP]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
HRP

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-26700AF350
Alexa Fluor 405
NBP3-26700AF405
Alexa Fluor 488
NBP3-26700AF488
Alexa Fluor 532
NBP3-26700AF532
Alexa Fluor 594
NBP3-26700AF594
Alexa Fluor 647
NBP3-26700AF647
Alexa Fluor 700
NBP3-26700AF700
Alexa Fluor 750
NBP3-26700AF750
Allophycocyanin
NBP3-26700APC
Biotin
NBP3-26700B
CoraFluor 1
NBP3-26700CL1
DyLight 350
NBP3-26700UV
DyLight 405
NBP3-26700V
DyLight 488
NBP3-26700G
DyLight 550
NBP3-26700R
DyLight 594
NBP3-26700DL594
DyLight 650
NBP3-26700C
DyLight 680
NBP3-26700FR
DyLight 755
NBP3-26700IR
FITC
NBP3-26700F
Janelia Fluor 525
NBP3-26700JF525
Janelia Fluor 549
NBP3-26700JF549
Janelia Fluor 646
NBP3-26700JF646
Janelia Fluor 669
NBP3-26700JF669
PE
NBP3-26700PE
PerCP
NBP3-26700PCP
Unconjugated
NBP3-26700
mFluor Violet 450 SE
NBP3-26700MFV450
mFluor Violet 500 SE
NBP3-26700MFV500
mFluor Violet 610 SE
NBP3-26700MFV610
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Optineurin Antibody [HRP] Summary

Immunogen
Partial recombinant protein made to an internal portion of human Optineurin between amino acids 150-350 [UniProt Q96CV9].
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
OPTN
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
No Preservative
Purity
Immunogen affinity purified

Alternate Names for Optineurin Antibody [HRP]

  • ALS12
  • FIP2
  • FIP2FIP-2
  • GLC1E
  • GLC1Eglaucoma 1, open angle, E (adult-onset)
  • HIP7
  • HIP7ALS12
  • Huntingtin interacting protein L
  • Huntingtin yeast partner L
  • Huntingtin-interacting protein 7
  • Huntingtin-interacting protein L
  • HYPL
  • HYPLHIP-7
  • NEMO-related protein
  • NRP
  • NRPE3-14.7K-interacting protein
  • Optic neuropathy-inducing protein
  • Optineurin
  • OPTN
  • TFIIIA-INTP
  • Transcription factor IIIA-interacting protein
  • transcrption factor IIIA-interacting protein
  • tumor necrosis factor alpha-inducible cellular protein containing leucinezipper domains

Background

Optineurin encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Optineurin
Antibody [HRP]
NBP3-26700H
Optineurin Antibody [HRP]
Species: Hu
Applications: WB, ICC/IF, IHC

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Bioinformatics

Gene Symbol OPTN