TDP-43/TARDBP Antibody (2E2-D3)

This product is produced by and distributed for Abnova, a company based in Taiwan.

HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 8 applications: ICC/IF, IF/IHC, IHC, IHC-P, IP, Immunohistochemistry, WB, Western Blot.

Showing Publications 1 - 10 of 211. Show All 211 Publications. Collapse Publications.

Publications using H00023435-M01	Applications	Species
Mamontova, EM;Clément, MJ;Sukhanova, MV;Joshi, V;Bouhss, A;Rengifo-Gonzalez, JC;Desforges, B;Hamon, L;Lavrik, OI;Pastré, D; FUS RRM regulates poly(ADP-ribose) levels after transcriptional arrest and PARP-1 activation on DNA damage Cell reports 2023-10-05 [PMID: 37804508]
Saheed A, Bin B, Emily T et al. Hyperglycemia and O-GlcNAc transferase activity drive a cancer stem cell pathway in triple-negative breast cancer. Cancer Cell Int. 2023-05-25 [PMID: 37231419]
Carmen-Orozco RP, Tsao W, Ye Y et al. Elevated nuclear TDP-43 induces constitutive exon skipping bioRxiv : the preprint server for biology 2023-05-12 [PMID: 37215013] (IHC, Mouse)	IHC	Mouse
Mandy K, Lale G, Renee S et al. Neuronal overexpression of hTDP-43 in Caenorhabditis elegans mimics the cellular pathology commonly observed in TDP-43 proteinopathies. MicroPubl Biol. 2023-04-19 [PMID: 37159575]
Toshihide T, Kazuhiro M, Xin D et al. Sustained therapeutic benefits by transient reduction of TDP-43 using ENA-modified antisense oligonucleotides in ALS/FTD mice. Mol Ther Nucleic Acids. 2023-01-16 [PMID: 36817728]
Ellen G, Simone B, Carlos N et al. Sporadic Creutzfeldt-Jakob disease VM1: phenotypic and molecular characterization of a novel subtype of human prion disease. Acta Neuropathol Commun. 2022-08-17 [PMID: 35978418]
Johnathan C, Thomas J, Emily F et al. Atypical TDP-43 protein expression in an ALS pedigree carrying a p.Y374X truncation mutation in TARDBP. Brain Pathol. 2022-07-24 [PMID: 35871544]
T Liu, JA Woo, MZ Bukhari, X Wang, Y Yan, SC Buosi, A Ermekbaeva, A Sista, P Kotsiviras, P LePochat, A Chacko, X Zhao, DE Kang Modulation of synaptic plasticity, motor unit physiology, and TDP-43 pathology by CHCHD10 Acta neuropathologica communications, 2022-07-04;10(1):95. 2022-07-04 [PMID: 35787294]
Krach F, Wheeler EC, Regensburger M Et al. Aberrant NOVA1 function disrupts alternative splicing in early stages of amyotrophic lateral sclerosis Acta Neuropathol 2022-07-01 [PMID: 35778567] (IHC-P, Human) Details: Citation using the Alexa Fluor 405 version of this antibody.	IHC-P	Human
Jorge M, Friederike H, Felix Z et al. Sirtuin-1 sensitive lysine-136 acetylation drives phase separation and pathological aggregation of TDP-43. Nat Commun. 2022-03-09 [PMID: 35264561]
Mashiko T, Sakashita E, Kasashima K et al. Developmentally-regulated RNA-binding protein 1 (Drb1)/RNA-binding motif protein 45 (RBM45), a nuclear-cytoplasmic trafficking protein, forms TAR DNA-binding protein 43 (TDP-43)-mediated cytoplasmic aggregates. JBC May 12 2016
Angelo J, Seong A A Microplate-Based Approach to Map Interactions between TDP-43 and ?-Synuclein. J Clin Med. 2022-01-24 [PMID: 35160025]
Kunikazu T, Fumiaki M, Fumiyuki S et al. Novel tankyrase inhibitors suppress TDP-43 aggregate formation. Biochem Biophys Res Commun. 2020-12-30 [PMID: 33387887]
Julien J, Swarup V., et al. Methods for Prognostic and/or Diagnostic of Neurodegenerative Disease, Method to Identify Candidate Compounds and Compounds for Treating Neurodegenerative Disease. United States Patent Application Mar 31 2016
Taylor P, Lauren F, Yu Z et al. Detection and characterization of TDP-43 in human cells and tissues by multiple reaction monitoring mass spectrometry. Clin Mass Spectrom. 2019-07-19 [PMID: 34917762]
Julien J, Swarup V. Methods for Prognostic and/or Diagnostic of Neurodegenerative Disease, Method to Identify Candidate Compounds and Compounds for Treating Neurodegenerative Disease. United States Patent Application. 2016-01-01
Aladesuyi Arogundade O Nucleolar Stress and RNA Toxicity in C9ORF72 Amyotrophic Lateral Sclerosis and Frontotemporal Dementia Thesis 2020-01-01 (ICC/IF, Human)	ICC/IF	Human
Harb K, Richter M, Neelagandan N et al. Pum2 and TDP-43 refine area-specific cytoarchitecture post-mitotically and modulate translation of Sox5, Bcl11b, and Rorb mRNAs in developing mouse neocortex eLife 2022-03-09 [PMID: 35262486] (WB, Mouse)	WB	Mouse
Teresa X, Alba M, Juan E et al. Homozygous R136S mutation in PRNP gene causes inherited early onset prion disease. Alzheimers Res Ther. 2021-10-18 [PMID: 34663460]
Yu-Ju L, Hung-Chih K, Yijuang C et al. A system-wide mislocalization of RNA-binding proteins in motor neurons is a new feature of ALS. Neurobiol Dis. 2021-10-09 [PMID: 34634461]
Karsten K, Maximilian W, Paula S et al. CSF Diagnostics: A Potentially Valuable Tool in Neurodegenerative and Inflammatory Disorders Involving Motor Neurons: A Review. Diagnostics (Basel). 2021-08-24 [PMID: 34573864]
Taylor P, David Y, Ian M et al. Aptamer-based enrichment of TDP-43 from human cells and tissues with quantification by HPLC-MS/MS. J Neurosci Methods. 2021-08-29 [PMID: 34469713]
Atkinson RAK, Fair HL, Wilson R et al. Effects of TDP-43 overexpression on neuron proteome and morphology in vitro Molecular and cellular neurosciences 2021-05-18 [PMID: 34015498]
Aladesuyi Arogundade O, Nguyen S, Leung R et al. Nucleolar stress in C9orf72 and sporadic ALS spinal motor neurons precedes TDP-43 mislocalization Acta neuropathologica communications 2021-02-15 [PMID: 33588953] (ICC/IF, Human)	ICC/IF	Human
Sunny K, Daniel P, Jean-Pierre J et al. Withaferin-A Treatment Alleviates TAR DNA-Binding Protein-43 Pathology and Improves Cognitive Function in a Mouse Model of FTLD. Neurotherapeutics. 2020-10-19 [PMID: 33078279]
Silvia P, Philippe C, Genevieve S et al. Monoclonal full-length antibody against TAR DNA-binding protein 43 reduces related proteinopathy in neurons. JCI Insight. 2020-11-05 [PMID: 33021970]
Shayna S, Zainuddin Q, Abraian M et al. Hypusination of Eif5a regulates cytoplasmic TDP-43 aggregation and accumulation in a stress-induced cellular model. Biochim Biophys Acta Mol Basis Dis. 2020-08-31 [PMID: 32882370]
Mishra P, Boutej H, Soucy G et al. Transmission of ALS pathogenesis by the cerebrospinal fluid. Acta Neuropathol Commun. 2020-05-07 [PMID: 32381112]
Shafei R, Woollacott I, Mummery C et al. Two pathologically confirmed cases of novel mutations in the MAPT gene causing frontotemporal dementia. Neurobiol Aging. 2019-11-20 [PMID: 31870644]
Zhao C, Devlin A, Chouhan A et al. Mutant C9orf72 human iPSC-derived astrocytes cause non-cell autonomous motor neuron pathophysiology. Glia. 2019-12-16 [PMID: 31841614]
Hans F, Glasebach H, Kahle P et al. Multiple distinct pathways lead to hyperubiquitylated insoluble TDP-43 protein independent of its translocation into stress granules. J Biol Chem. 2019-11-28 [PMID: 31780563]
Verheijen B, Lussier C, Muller-Hubers C et al. Activation of the Unfolded Protein Response and Proteostasis Disturbance in Parkinsonism-Dementia of Guam. J Neuropathol Exp Neurol. 2020-01-01 [PMID: 31750913]
Ahmed S, Fairen M, Sabir M et al. MAPT p.V363I mutation: A rare cause of corticobasal degeneration. Neurol Genet. 2019-06-25 [PMID: 31404212]
Martinez-Valbuena I, Valenti-Azcarate R, Amat-Villegas I et al. Amylin as a potential link between type 2 diabetes and alzheimer disease. Ann Neurol. 2019-08-03 [PMID: 31376172]
Miki Y, Foti S, Asi Y et al. Improving diagnostic accuracy of multiple system atrophy: a clinicopathological study. Brain. 2019-07-09 [PMID: 31289815]
Francesco G, Anna L, Tiziana A et al. Autophagy markers LC3 and p62 accumulate in immune-mediated necrotizing myopathy. Muscle Nerve. 2019-06-21 [PMID: 31172530]
Cortese A, Simone R, Sullivan R et al. Biallelic expansion of an intronic repeat in RFC1 is a common cause of late-onset ataxia Nat. Genet. 2019-04-01 [PMID: 30926972] (IHC-P, Human)	IHC-P	Human
Yin P, Guo X, Yang W et al. Caspase-4 mediates cytoplasmic accumulation of TDP-43 in the primate brains. Acta Neuropathol. 2019-02-27 [PMID: 30810811]
Kim G, Bolbolan K, Shahidehpour R et al. Morphology and Distribution of TDP-43 Pre-inclusions in Primary Progressive Aphasia. J Neuropathol Exp Neurol. 2019-02-08 [PMID: 30753613]
Yamashita T, Kato H, Kimura T, and Kwak S Impaired Nucleoporins Are Present in Sporadic Amyotrophic Lateral Sclerosis Motor Neurons that Exhibit Mislocalization of the 43-kDa TAR DNA-Binding Protein. J Clin Neurol. 2019-03-04 [PMID: 30618218]
Gomez-Tortosa E, Baradaran-Heravi Y, Gonzalez Alvarez V et al. Presence of tau astrogliopathy in frontotemporal dementia caused by a novel Grn nonsense (Trp2*) mutation. Neurobiol Aging. 2019-01-03 [PMID: 30545478]
Thammisetty SS, Pedragosa J, Weng YC et al. Age-related deregulation of TDP-43 after stroke enhances NF-?B-mediated inflammation and neuronal damage. J Neuroinflammation 2018-11-09 [PMID: 30413172]
Steinacker P, Barschke P, Otto M. et al. Biomarkers for diseases with TDP-43 pathology. Mol Cell Neurosci 2018-11-03 [PMID: 30399416]
Neelagandan N, Gonnella G, Dang S et al. TDP-43 enhances translation of specific mRNAs linked to neurodegenerative disease. Nucleic Acids Res. 2018-10-24 [PMID: 30357366] (WB, Mouse)	WB	Mouse
Vicente-Pascual M, Rossi M, Gamez J et al. Variably protease-sensitive prionopathy presenting within ALS/FTD spectrum. Ann Clin Transl Neurol. 2018-10-15 [PMID: 30349865]
Solomon DA, Stepto A, Au WH et al. A feedback loop between dipeptide-repeat protein, TDP-43 and karyopherin-? mediates C9orf72-related neurodegeneration. Brain 2018-10-01 [PMID: 30239641]
Ramos-Campoy O, Avila-Polo R, Grau-Rivera O et al. Systematic Screening of Ubiquitin/p62 Aggregates in Cerebellar Cortex Expands the Neuropathological Phenotype of the C9orf72 Expansion Mutation. J Neuropathol Exp Neurol 2018-06-07 [PMID: 29889265]
Pozzi S, Thammisetty SS, Julien JP. et al. Chronic Administration of Pimozide Fails to Attenuate Motor and Pathological Deficits in Two Mouse Models of Amyotrophic Lateral Sclerosis. Neurotherapeutics 2018-05-22 [PMID: 29790082]
Andres-Benito P, Gelpi E, Povedano M et al. Gene Expression Profile in Frontal Cortex in Sporadic Frontotemporal Lobar Degeneration-TDP. J Neuropathol Exp Neurol 2018-05-19 [PMID: 29788265]
Scherz B, Rabl R, Flunkert S et al. mTh1 driven expression of hTDP-43 results in typical ALS/FTLD neuropathological symptoms. PLoS One 2018-05-22 [PMID: 29787578]
Endo R, Takashima N, Nekooki-Machida Y et al. TAR DNA-Binding Protein 43 and Disrupted in Schizophrenia 1 Coaggregation Disrupts Dendritic Local Translation and Mental Function in Frontotemporal Lobar Degeneration. Biol Psychiatry 2018-03-29 [PMID: 29752072]
Verheijen B, Oyanagi K, van F et al. Dysfunction of Protein Quality Control in Parkinsonism-Dementia Complex of Guam. Front Neurol. 2018-03-20 [PMID: 29615966]
Lai C, Liu Y, Lai H et al. The D2 Dopamine Receptor Interferes With the Protective Effect of the A2A Adenosine Receptor on TDP-43 Mislocalization in Experimental Models of Motor Neuron Degeneration. Front Neurosci. 2018-03-20 [PMID: 29615863]
Deshaies JE, Shkreta L, Moszczynski AJ et al. TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis. Brain 2018-03-19 [PMID: 29562314]
Grames MS, Dayton RD, Jackson KL et al. Cre-dependent AAV vectors for highly targeted expression of disease-related proteins and neurodegeneration in the substantia nigra. FASEB J 2018-03-07 [PMID: 29513569]
Giannoccaro MP, Bartoletti-Stella A, Piras S et al. The First Historically Reported Italian Family with FTD/ALS Teaches a Lesson on C9orf72 RE: Clinical Heterogeneity and Oligogenic Inheritance. J Alzheimers Dis 2018-02-20 [PMID: 29480190]
Feneberg E, Gray E, Ansorge O et al. Towards a TDP-43-Based Biomarker for ALS and FTLD. Mol Neurobiol 2018-02-19 [PMID: 29460270]
Berson A, Sartoris A, Nativio R et al. TDP-43 Promotes Neurodegeneration by Impairing Chromatin Remodeling Curr. Biol. 2017-11-09 [PMID: 29153328] (Human)		Human
St-Amour I, Turgeon A, Goupil C et al. Co-occurrence of mixed proteinopathies in late-stage Huntingtons disease. Acta Neuropathol 2017-11-13 [PMID: 29134321]
Gregory JM, Whiten DR, Brown RA et al. Clusterin protects neurons against intracellular proteotoxicity. Acta Neuropathol Commun 2017-11-07 [PMID: 29115989]
Borrego-Ecija S, Morgado J, Palencia-Madrid L et al. Frontotemporal Dementia Caused by the P301L Mutation in the MAPT Gene: Clinicopathological Features of 13 Cases from the Same Geographical Origin in Barcelona, Spain. Dement Geriatr Cogn Disord 2017-09-22 [PMID: 28934750]
Gelpi E, Carrato C, Grau-Lopez L et al. Incidental neuronal intermediate filament inclusion pathology: unexpected biopsy findings in a 37-year old woman with epilepsy. Neuropathol Appl Neurobiol 2017-09-07 [PMID: 28880406]
Chang JC, Morton DB. Drosophila lines with mutant and wild type human TDP-43 replacing the endogenous gene reveals phosphorylation and ubiquitination in mutant lines in the absence of viability or lifespan defects. PLoS One 2017-07-07 [PMID: 28686708]
Moreno F, Indakoetxea B, Barandiaran M et al. The unexpected co-occurrence of GRN and MAPT p.A152T in Basque families: Clinical and pathological characteristics. PLoS One 2017-06-08 [PMID: 28594853]
Ash PEA, Stanford EA, Al Abdulatif A et al. Dioxins and related environmental contaminants increase TDP-43 levels. Mol Neurodegener 2017-05-05 [PMID: 28476168]
Becker LA, Huang B, Bieri G et al. Therapeutic reduction of ataxin-2 extends lifespan and reduces pathology in TDP-43 mice Nature 2017-04-20 [PMID: 28405022] (Immunohistochemistry, Western Blot)	Immunohistochemistry, Western Blot
Koriath CAM, Bocchetta M, Brotherhood E et al. The clinical, neuroanatomical, and neuropathologic phenotype of TBK1-associated frontotemporal dementia: A longitudinal case report. Alzheimers & Dementia: Diagnosis, Assessment & Disease Monitoring 2016-11-03 [PMID: 28229125]
Wang W, Arakawa H, Wang L et al. Motor-Coordinative and Cognitive Dysfunction Caused by Mutant TDP-43 Could Be Reversed by Inhibiting Its Mitochondrial Localization. Mol Ther 2017-01-04 [PMID: 28129109]
van der Zee J, Gijselinck I, Van Mossevelde S et al. TBK1 Mutation Spectrum in an Extended European Patient Cohort With Frontotemporal Dementia and Amyotrophic Lateral Sclerosis. Hum Mutat 2016-12-23 [PMID: 28008748]
Redaelli V, Rossi G, Maderna E et al. Alzheimer neuropathology without frontotemporal lobar degeneration hallmarks (TAR DNA-binding protein 43 inclusions) in missense progranulin mutation Cys139Arg. Brain Pathol 2016-12-20 [PMID: 27997711]
Dutta K, Patel P, Rahimian R et al. Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration. Neurotherapeutics 2016-12-07 [PMID: 27928708]
Gelpi E, Hoftberger R, Graus F et al. Neuropathological criteria of anti-IgLON5-related tauopathy. Acta Neuropathol 2016-06-29 [PMID: 27358064]
Wang W, Wang L, Lu J et al. The inhibition of TDP-43 mitochondrial localization blocks its neuronal toxicity. Nat Med 2016-08-01 [PMID: 27348499]
Ansoleaga B, Garcia-Esparcia P, Llorens F et al. Altered Mitochondria, Protein Synthesis Machinery, and Purine Metabolism Are Molecular Contributors to the Pathogenesis of Creutzfeldt-Jakob Disease. J Neuropathol Exp Neurol 2016-06-12 [PMID: 27297670]
Koyama A, Sugai A, Kato T et al. Increased cytoplasmic TARDBP mRNA in affected spinal motor neurons in ALS caused by abnormal autoregulation of TDP-43. Nucleic Acids Res 2016-07-08 [PMID: 27257061] (WB)	WB
Mashiko T, Sakashita E, Kasashima K et al. Developmentally Regulated RNA-binding Protein 1 (Drb1)/RNA-binding Motif Protein 45 (RBM45), a Nuclear-Cytoplasmic Trafficking Protein, Forms TAR DNA-binding Protein 43 (TDP-43)-mediated Cytoplasmic Aggregates. J Biol Chem 2016-05-12 [PMID: 27226551]
De Marco G, Lomartire A, Calvo A et al. Monocytes of patients with amyotrophic lateral sclerosis linked to gene mutations display altered TDP-43 subcellular distribution. Neuropathol Appl Neurobiol 2016-05-14 [PMID: 27178390]
Williams KL, Topp S, Yang S et al. CCNF mutations in amyotrophic lateral sclerosis and frontotemporal dementia. Nat Commun 2016-04-15 [PMID: 27080313] (IP)	IP
Jiang LL, Zhao J, Yin XF et al. Two mutations G335D and Q343R within the amyloidogenic core region of TDP-43 influence its aggregation and inclusion formation. Sci Rep 2016-03-31 [PMID: 27030292]
Solla P, Grau O, Gelpi E et al. Pisa syndrome in a patient with pathologically confirmed Parkinsons disease. Neuropathol Appl Neurobiol 2016-04-28 [PMID: 26999006]
Wang G, Yang H, Yan S et al. Cytoplasmic mislocalization of RNA splicing factors and aberrant neuronal gene splicing in TDP-43 transgenic pig brain. Mol Neurodegener. 2015-09-03 [PMID: 26334913]
Lynch DS, Jaunmuktane Z, Sheerin UM et al. Hereditary leukoencephalopathy with axonal spheroids: a spectrum of phenotypes from CNS vasculitis to parkinsonism in an adult onset leukodystrophy series. J Neurol Neurosurg Psychiatry 2016-05-01 [PMID: 25935893]
Goossens J, Vanmechelen E, Trojanowski JQ et al. TDP-43 as a possible biomarker for frontotemporal lobar degeneration: a systematic review of existing antibodies Acta Neuropathol Commun 2015-04-09 [PMID: 25853864] Details: This publication is a systematic review of existing antibodies for TDP-43/TARDBP.
Xiao S, Sanelli T, Chiang H et al. Low molecular weight species of TDP-43 generated by abnormal splicing form inclusions in amyotrophic lateral sclerosis and result in motor neuron death. Acta Neuropathol. 2015-03-19 [PMID: 25788357] (IHC-P, Human)	IHC-P	Human
Rosenbohm A, Buckert D, Gerischer N et al. Early diagnosis of cardiac involvement in idiopathic inflammatory myopathy by cardiac magnetic resonance tomography. J Neurol. 2015-02-12 [PMID: 25673126]
Saldi TK, Ash PE, Wilson G et al. TDP-1, the Caenorhabditis elegans ortholog of TDP-43, limits the accumulation of double-stranded RNA. EMBO J. 2014-11-12 [PMID: 25391662]
Alafuzoff I, Pikkarainen M, Neumann M et al. Neuropathological assessments of the pathology in frontotemporal lobar degeneration with TDP43-positive inclusions: an inter-laboratory study by the BrainNet Europe consortium. J Neural Transm. 2014-09-20 [PMID: 25239189]
Yarchoan M, Toledo JB, Lee EB et al. Abnormal serine phosphorylation of insulin receptor substrate 1 is associated with tau pathology in Alzheimer's disease and tauopathies. Acta Neuropathol. 2014-08-09 [PMID: 25107476] (IHC-P, Human)	IHC-P	Human
Kara Eleanna, Kiely Aoife P, Proukakis Christos et al. A 6.4 Mb duplication of the alpha-synuclein locus causing frontotemporal dementia and Parkinsonism: phenotype-genotype correlations. JAMA Neurol. 2014-09-01 [PMID: 25003242] (Human)		Human
Robinson AC, Thompson JC, Weedon L et al. No interaction between tau and TDP-43 pathologies in either frontotemporal lobar degeneration or motor neurone disease. Neuropathol Appl Neurobiol. 2014-04-15 [PMID: 24861427]
Chen W, Lonskaya I, Hebron ML et al. Parkin-mediated reduction of nuclear and soluble TDP-43 reverses behavioral decline in symptomatic mice. Hum. Mol. Genet. 2013-01-01 [PMID: 24847002]
Hans F, Fiesel FC, Strong JC et al. UBE2E Ubiquitin-conjugating Enzymes and Ubiquitin Isopeptidase Y Regulate TDP-43 Protein Ubiquitination. J Biol Chem. 2014-05-13 [PMID: 24825905]
Ohta Y, Tremblay C, Schneider JA et al. Interaction of transactive response DNA binding protein 43 with nuclear factor kappaB in mild cognitive impairment with episodic memory deficits. Acta Neuropathol Commun. 2014-04-01 [PMID: 24690380]
Carlomagno Y, Zhang Y, Davis M et al. Casein Kinase II Induced Polymerization of Soluble TDP-43 into Filaments Is Inhibited by Heat Shock Proteins. PLoS One. 2014-03-04 [PMID: 24595055]
Araki W, Minegishi S, Motoki K et al. Disease-Associated Mutations of TDP-43 Promote Turnover of the Protein Through the Proteasomal Pathway. Mol Neurobiol. 2014-01-30 [PMID: 24477737]
Cortese A, Plagnol V, Brady S et al. Widespread RNA metabolism impairment in sporadic inclusion body myositis TDP43-proteinopathy. Neurobiol Aging. 2013-12-30 [PMID: 24462217]
De Marco Giovanni, Lomartire Annarosa, Mandili Giorgia et al. Reduced cellular Ca(2+) availability enhances TDP-43 cleavage by apoptotic caspases. Biochim Biophys Acta. 2014-01-16 [PMID: 24440855] (WB)	WB
Gelpi E, Navarro-Otano J, Tolosa E et al. Multiple organ involvement by alpha-synuclein pathology in Lewy body disorders. Mov Disord. 2014-01-02 [PMID: 24395122]
Yan S, Wang CE, Wei W et al. TDP-43 Causes Differential Pathology in Neuronal versus Glial Cells in the Mouse Brain. Hum Mol Genet. 2014-01-10 [PMID: 24381309]
Balasa M, Gelpi E, Rey MJ et al. Clinical And Neuropathological Variability In Clinically Isolated Central Nervous System Whipple's Disease. Brain Pathol. 2014-01-13 [PMID: 24320005]
Walker AK, Soo KY, Sundaramoorthy V et al. ALS-Associated TDP-43 Induces Endoplasmic Reticulum Stress, Which Drives Cytoplasmic TDP-43 Accumulation and Stress Granule Formation. PLoS One. 2013-11-29 [PMID: 24312274]
Suarez-Calvet M, Dols-Icardo O, Llado A et al. Plasma phosphorylated TDP-43 levels are elevated in patients with frontotemporal dementia carrying a C9orf72 repeat expansion or a GRN mutation. J Neurol Neurosurg Psychiatry. 2013-12-04 [PMID: 24309270]
Hebron M, Chen W, Miessau MJ et al. Parkin reverses TDP-43-induced cell death and failure of amino acid homeostasis. J Neurochem. 2013-12-02 [PMID: 24298989]
Iovino M, Pfisterer U, Holton JL et al. The novel MAPT mutation K298E: mechanisms of mutant tau toxicity, brain pathology and tau expression in induced fibroblast-derived neurons. Acta Neuropathol. 2013-11-30 [PMID: 24292008]
Lashley T, Rohrer JD, Mahoney C et al. A pathogenic progranulin mutation and C9orf72 repeat expansion in a family with frontotemporal dementia. Neuropathol Appl Neurobiol. 2014-06-01 [PMID: 24286341]
Grau-Rivera O, Gelpi E, Rey MJ et al. Prominent psychiatric symptoms in patients with Parkinson's disease and concomitant argyrophilic grain disease. J Neurol. 2013-09-18 [PMID: 24046066]
Medina DX, Orr ME, Oddo S. Accumulation of C-terminal fragments of transactive response DNA-binding protein 43 leads to synaptic loss and cognitive deficits in human TDP-43 transgenic mice. Neurobiol Aging. 2013-08-15 [PMID: 23954172] (WB, ICC/IF, IF/IHC, Mouse)	WB, ICC/IF, IF/IHC	Mouse
Xu YF, Prudencio M, Hubbard JM et al. The Pathological Phenotypes of Human TDP-43 Transgenic Mouse Models Are Independent of Downregulation of Mouse Tdp-43. PLoS One 2013-07-26 [PMID: 23922830] (WB, Mouse)	WB	Mouse
Prell T, Grosskreutz J. The involvement of the cerebellum in amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener 2013-12-01 [PMID: 23889583] (IF/IHC, Human)	IF/IHC	Human
Finsterer J, Stollberger C, Kovacs GG. Asymptomatic hyper-creatine-kinase-emia as sole manifestation of inclusion body myositis. Neurol Int. 2013-06-25 [PMID: 23888214]
Nishimoto Y, Nakagawa S, Hirose T et al. The long non-coding RNA nuclear-enriched abundant transcript 1_2 induces paraspeckle formation in the motor neuron during the early phase of amyotrophic lateral sclerosis. Mol Brain. 2013-01-01 [PMID: 23835137] (IP)	IP
Mundinano IC, Hernandez M, Dicaudo C et al. Reduced cholinergic olfactory centrifugal inputs in patients with neurodegenerative disorders and MPTP-treated monkeys. Acta Neuropathol. 2013-06-20 [PMID: 23784261]
Tong J, Huang C, Bi F et al. Expression of ALS-linked TDP-43 mutant in astrocytes causes non-cell-autonomous motor neuron death in rats. EMBO J. 2013-05-28 [PMID: 23714777]
Gelpi E, Cullel F, Navarro-Otano J, Llado A. Globular glial-like inclusions in a patient with advanced Alzheimer's disease. Acta Neuropathol. 2013-05-23 [PMID: 23700215]
Dayton RD, Gitcho MA, Orchard EA et al. Selective Forelimb Impairment in Rats Expressing a Pathological TDP-43 25 kDa C-terminal Fragment to Mimic Amyotrophic Lateral Sclerosis. Mol Ther. 2013-05-21 [PMID: 23689600]
Iyer A, Prabowo A, Anink J et al. Cell injury and premature neurodegeneration in focal malformations of cortical development. Brain Pathol. 2013-03-11 [PMID: 23586324]
Iranzo A, Tolosa E, Gelpi E et al. Neurodegenerative disease status and post-mortem pathology in idiopathic rapid-eye-movement sleep behaviour disorder: an observational cohort study. Lancet Neurol. 2013-03-06 [PMID: 23562390]
Bi F, Huang C, Tong J et al. Reactive astrocytes secrete lcn2 to promote neuron death. Proc Natl Acad Sci U S A. 2013-02-19 [PMID: 23431168]
Doherty KM, Rohrer JD, Lees AJ et al. Primary progressive aphasia with parkinsonism: Clinicopathological case. Mov Disord. 2013-02-11 [PMID: 23401267]
Hebron ML, Lonskaya I, Sharpe K et al. Parkin Ubiquitinates Tar-DNA Binding Protein-43 (TDP-43) and Promotes Its Cytosolic Accumulation via Interaction with Histone Deacetylase 6 (HDAC6). J Biol Chem. 2012-12-20 [PMID: 23258539]
Swarup V, Audet JN, Phaneuf D et al. Abnormal Regenerative Responses and Impaired Axonal Outgrowth after Nerve Crush in TDP-43 Transgenic Mouse Models of Amyotrophic Lateral Sclerosis. J Neurosci. 2013-01-08 [PMID: 23238732]
Watanabe S, Kaneko K, Yamanaka K. Accelerated Disease Onset with Stabilized Familial Amyotrophic Lateral Sclerosis (ALS)-linked Mutant TDP-43 Proteins. J Biol Chem. 2012-12-12 [PMID: 23235148]
Tong J, Huang C, Bi F et al. XBP1 Depletion Precedes Ubiquitin Aggregation and Golgi Fragmentation in TDP-43 Transgenic Rats. J Neurochem. 2012-11-01 [PMID: 22970712]
Lopez-Gonzalez I, Carmona M, Blanco R et al. Characterization of Thorn-Shaped Astrocytes in White Matter of Temporal Lobe in Alzheimer's Disease Brains. Brain Pathol. 2012-08-13 [PMID: 22882361]
Verstraete E, Kuiperij HB, van Blitterswijk MM et al. TDP-43 plasma levels are higher in amyotrophic lateral sclerosis. Amyotroph Lateral Scler. 2012-08-08 [PMID: 22873561]
Gelpi E, Soler Insa JM, Parchi P et al. Atypical neuropathological sCJD-MM phenotype with abundant white matter Kuru-type plaques sparing the cerebellar cortex. Neuropathology. 2012-05-18 [PMID: 22862687]
Colom-Cadena M, Gelpi E, Marti MJ et al. MAPT H1 haplotype is associated with enhanced alpha-synuclein deposition in dementia with Lewy bodies. Neurobiol Aging. 2012-06-21 [PMID: 22819391]
Vilas D, Marti MJ, Botta-Orfila T et al. Pick's pathology in Parkinson's disease with dementia. Neuropathol Appl Neurobiol. 2012-06-12 [PMID: 22686686]
Echavarri C, Burgmans S, Caballero MC et al. Co-occurrence of Different Pathologies in Dementia: Implications for Dementia Diagnosis. J Alzheimers Dis. 2012-04-10 [PMID: 22495343]
Herman AM, Khandelwal PJ, Rebeck GW, Moussa CE. Wild Type TDP-43 Induces Neuro-Inflammation and Alters APP Metabolism in Lentiviral Gene Transfer Models. Exp Neurol. 2012-02-28 [PMID: 22402344]
Troakes C, Maekawa S, Wijesekera L et al. An MND/ALS phenotype associated with C9orf72 repeat expansion: Abundant p62-positive, TDP-43-negative inclusions in cerebral cortex, hippocampus and cerebellum but without associated cognitive decline. Neuropathology. 2011-12-19 [PMID: 22181065]
Dayton RD, Wang DB, Cain CD et al. Frontotemporal lobar degeneration related proteins induce only subtle memory-related deficits when bilaterally overexpressed in the dorsal hippocampus. Exp Neurol. 2011-12-09 [PMID: 22177996]
Huang C, Tong J, Bi F et al. Mutant TDP-43 in motor neurons promotes the onset and progression of ALS in rats. J Clin Invest. 2011-12-12 [PMID: 22156203]
Pirici D, Pirici I, Mogoanta L et al. Matrix metalloproteinase-9 expression in the nuclear compartment of neurons and glial cells in aging and stroke Neuropathology 2012-10-01 [PMID: 22151540] (IHC-P, Rat)	IHC-P	Rat
Tsuji H, Nonaka T, Yamashita M et al. Epitope mapping of antibodies against TDP-43 and detection of protease-resistant fragments of pathological TDP-43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration. Biochem Biophys Res Commun. 2011-11-22 [PMID: 22133678]
Fiesel FC, Weber SS, Supper J et al. TDP-43 regulates global translational yield by splicing of exon junction complex component SKAR. Nucleic Acids Res. 2011-11-25 [PMID: 22121224]
Antonell A, Gelpi E, Sanchez-Valle R et al. Breakpoint Sequence Analysis of an AbPP Locus Duplication Associated with Autosomal Dominant Alzheimers Disease and Severe Cerebral Amyloid Angiopathy. J Alzheimers Dis. 2011-10-18 [PMID: 22008262]
Thom M, Liu JY, Thompson P et al. Neurofibrillary tangle pathology and Braak staging in chronic epilepsy in relation to traumatic brain injury and hippocampal sclerosis: a post-mortem study. Brain. 2011-09-08 [PMID: 21903728]
Wang JW, Brent JR, Tomlinson A et al. The ALS-associated proteins FUS and TDP-43 function together to affect Drosophila locomotion and life span. J Clin Invest. 2011-09-01 [PMID: 21881207]
Swarup V, Phaneuf D, Bareil C et al. Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments. Brain. 2011-07-13 [PMID: 21752789]
Martinez-Saez E, Gelpi E, Rey M et al. Hirano body - rich subtypes of Creutzfeldt-Jakob disease. Neuropathol Appl Neurobiol. 2011-07-05 [PMID: 21726270]
Azizi AA, Li L, Strobel T et al. Identification of c-myc-dependent proteins in the medulloblastoma cell line D425Med. Amino Acids 2011-06-12 [PMID: 21667264]
Lopez-Hernandez T, Sirisi S, Capdevila-Nortes X et al. Molecular mechanisms of MLC1 and GLIALCAM mutations in megalencephalic leukoencephalopathy with subcortical cysts. Hum Mol Genet. 2011-06-07 [PMID: 21624973]
Rusina R, Kovacs GG, Fiala J et al. FTLD-TDP with motor neuron disease, visuospatial impairment and a progressive supranuclear palsy-like syndrome: broadening the clinical phenotype of TDP-43 proteinopathies. A report of three cases. BMC Neurol. 2011-05-10 [PMID: 21569259]
Mundinano IC, Caballero MC, Ordonez C et al. Increased dopaminergic cells and protein aggregates in the olfactory bulb of patients with neurodegenerative disorders. Acta Neuropathol. 2011-05-08 [PMID: 21553300]
Pikkarainen M, Hartikainen P, Soininen H, Alafuzoff I. Distribution and Pattern of Pathology in Subjects with Familial or Sporadic Late-Onset Cerebellar Ataxia as Assessed by p62/Sequestosome Immunohistochemistry. Cerebellum. 2011-05-05 [PMID: 21544590]
Hartikainen PH, Pikkarainen M, Hanninen T et al. Unusual clinical presentation and neuropathology in two subjects with fused-in sarcoma (FUS) positive inclusions. Neuropathology. 2012-02-01 [PMID: 21518013] (Human)		Human
Che MX, Jiang YJ, Xie YY et al. Aggregation of the 35-kDa fragment of TDP-43 causes formation of cytoplasmic inclusions and alteration of RNA processing. FASEB J. 2011-04-08 [PMID: 21450909]
Tian T, Huang C, Tong J et al. TDP-43 Potentiates Alpha-synuclein Toxicity to Dopaminergic Neurons in Transgenic Mice. Int J Biol Sci. 2011-03-04 [PMID: 21448284]
Herman AM, Khandelwal PJ, Stanczyk BB et al. Beta-amyloid triggers ALS-associated TDP-43 pathology in AD models. Brain Res. 2011-03-01 [PMID: 21376022]
Lashley T, Holton JL, Revesz T. TDP-43 pathology may occur in the BRI2 gene-related dementias. Acta Neuropathol. 2011-02-22 [PMID: 21340582]
Rauramaa T, Pikkarainen M, Englund E et al. TAR-DNA binding protein-43 and alterations in the hippocampus. J Neural Transm. 2011-01-06 [PMID: 21210283]
Noto Y, Shibuya K, Sato Y et al. Elevated CSF TDP-43 levels in amyotrophic lateral sclerosis: specificity, sensitivity, and a possible prognostic value. Amyotroph Lateral Scler 2011-03-01 [PMID: 21126161]
De Marco G, Lupino E, Calvo A et al. Cytoplasmic accumulation of TDP-43 in circulating lymphomonocytes of ALS patients with and without TARDBP mutations. Acta Neuropathol. 2010-12-01 [PMID: 21120508]
Higashi S, Tsuchiya Y, Araki T, Wada K, Kabuta T. TDP-43 physically interacts with amyotrophic lateral sclerosis-linked mutant CuZn superoxide dismutase. Neurochem Int 57(8):906-13. 2010-12-01 [PMID: 20933032]
Wang DB, Dayton RD, Henning PP et al. Expansive Gene Transfer in the Rat CNS Rapidly Produces Amyotrophic Lateral Sclerosis Relevant Sequelae When TDP-43 is Overexpressed. Mol Ther. 2010-09-28 [PMID: 20877346]
Hoftberger R, Fink S, Aboul-Enein F et al. Tubulin polymerization promoting protein (TPPP/p25) as a marker for oligodendroglial changes in multiple sclerosis. Glia 58(15):1847-57. 2010-11-15 [PMID: 20737479]
Shan X, Chiang PM, Price DL, Wong PC. Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. Proc Natl Acad Sci U S A 2010-09-14 [PMID: 20736350] (WB, Mouse)	WB	Mouse
Xu YF, Gendron TF, Zhang YJ et al. Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice. J Neurosci. 2010-08-11 [PMID: 20702714] (WB, IF/IHC, ICC/IF, Mouse) Details: WB: Mouse brain cells, Fig 5E.	WB, IF/IHC, ICC/IF	Mouse
Ling SC, Albuquerque CP, Han JS et al. ALS-associated mutations in TDP-43 increase its stability and promote TDP-43 complexes with FUS/TLS. Proc Natl Acad Sci U S A. 2010-07-12 [PMID: 20624952]
Saito T, Hanai S, Takashima S et al. Neocortical Layer Formation of Human Developing Brains and Lissencephalies: Consideration of Layer-Specific Marker Expression. Cereb Cortex. 2010-07-12 [PMID: 20624841]
Jansen C, Head MW, van Gool WA et al. The first case of protease-sensitive prionopathy (PSPr) in The Netherlands: a patient with an unusual GSS-like clinical phenotype. J Neurol Neurosurg Psychiatry. 2010-06-14 [PMID: 20547632]
Ash PE, Zhang YJ, Roberts CM et al. Neurotoxic effects of TDP-43 overexpression in C. Hum Mol Genet. 19(16):3206-18. 2010-08-15 [PMID: 20530643]
Maruyama H, Morino H, Ito H et al. Mutations of optineurin in amyotrophic lateral sclerosis. Nature. 2010-04-18 [PMID: 20428114]
Braak H, Ludolph A, Thal DR et al. Amyotrophic lateral sclerosis: dash-like accumulation of phosphorylated TDP-43 in somatodendritic and axonal compartments of somatomotor neurons of the lower brainstem and spinal cord. Acta Neuropathol 120(1):67-74. 2010-07-01 [PMID: 20379728]
Ilieva EV, Naudi A, Kichev A et al. Depletion of oxidative and endoplasmic reticulum stress regulators in Pick disease. Free Radic Biol Med. 2010-02-20 [PMID: 20176102]
Wils H, Kleinberger G, Janssens J et al. TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration. Proc Natl Acad Sci U S A 107(8):3858-63. 2010-02-23 [PMID: 20133711]
Zhang HX, Tanji K, Yoshida H et al. Alteration of biochemical and pathological properties of TDP-43 protein by a lipid mediator, 15-deoxy-Delta(12,14)-prostaglandin J(2). Exp Neurol 222(2):296-303. 2010-04-01 [PMID: 20083106]
Fiesel FC, Voigt A, Weber SS et al. Knockdown of transactive response DNA-binding protein (TDP-43) downregulates histone deacetylase 6. EMBO J 29(1):209-21. 2010-01-06 [PMID: 19910924]
Nishimoto Y, Ito D, Yagi T et al. Characterization of alternative isoforms and inclusion body of the TAR DNA-binding protein-43. J Biol Chem 285(1):608-19. 2010-01-01 [PMID: 19887443]
Foulds PG, Davidson Y, Mishra M et al. Plasma phosphorylated-TDP-43 protein levels correlate with brain pathology in frontotemporal lobar degeneration. Acta Neuropathol. 2009-10-13 [PMID: 19823856]
Velakoulis D, Walterfang M, Mocellin R et al. Abnormal hippocampal distribution of TDP-43 in patients with-late onset psychosis. Aust N Z J Psychiatry. 2009-08-01 [PMID: 19629795]
Moisse K, Mepham J, Volkening K et al. Cytosolic TDP-43 expression following axotomy is associated with caspase 3 activation in NFL-/- mice: support for a role for TDP-43 in the physiological response to neuronal injury. Brain Res 1296:176-86. 2009-11-03 [PMID: 19619516]
Velakoulis D, Walterfang M, Mocellin R et al. Frontotemporal dementia presenting as schizophrenia-like psychosis in young people: clinicopathological series review of cases. Br J Psychiatry 194(4):298-305. 2009-04-01 [PMID: 19336778]
Humayun S, Gohar M, Volkening K et al. The complement factor C5a receptor is upregulated in NFL-/- mouse motor neurons. J Neuroimmunol. 2009-03-13 [PMID: 19286267]
Gitcho MA, Strider J, Carter D et al. VCP mutations causing frontotemporal lobar degeneration disrupt localization of TDP-43 induce cell death . J Biol Chem. 2009-02-23 [PMID: 19237541]
Olive M, Janue A, Moreno D et al. TAR DNA-Binding Protein 43 Accumulation in Protein Aggregate Myopathies. J Neuropathol Exp Neurol. 2009-03-01 [PMID: 19225410]
Rollinson S, Rizzu P, Sikkink S et al. Ubiquitin associated protein 1 is a risk factor for frontotemporal lobar degeneration. Neurobiol Aging 30(4):656-65. 2009-04-01 [PMID: 19217189]
Igaz LM, Kwong LK, Chen-Plotkin A et al. Expression Of TDP-43 C-terminal fragments in vitro recapitulates pathological features of TDP-43 proteinopathies. J Biol Chem;284(13):8516-24. 2009-03-27 [PMID: 19164285]
Clarimon J, Molina-Porcel L, Gomez-Isla T et al. Early-Onset Familial Lewy Body Dementia With Extensive Tauopathy: A Clinical, Genetic, and Neuropathological Study. J Neuropathol Exp Neurol. 2009-01-01 [PMID: 19104444]
Moisse K, Volkening K, Leystra-Lantz C et al. Divergent patterns of cytosolic TDP-43 neuronal progranulin expression following axotomy: Implications for TDP-43 in the physiological response to neuronal injury. Brain Research ,doi:10.1016/j.brainres.2008.10.021. 2008-01-01 [PMID: 19046946]
Schwab C, Arai T, Hasegawa M et al. Colocalization of Transactivation-Responsive DNA-Binding Protein 43 and Huntingtin in Inclusions of Huntington Disease. J Neuropathol Exp Neurol 2008-12-01 [PMID: 19018245]
Steinacker P, Hendrich C, Sperfeld AD et al. TDP-43 in Cerebrospinal Fluid of Patients With Frontotemporal Lobar Degeneration and Amyotrophic Lateral Sclerosis. Arch Neurol. 2008-11-01 [PMID: 19001167]
Seppanen A, Pikkarainen M, Hartikainen P et al. Expression of collagen XVII ubiquitin-binding protein p62 in motor neuron disease. Brain Res;1247:171-7. 2009-01-09 [PMID: 18992722]
Kasai T, Tokuda T, Ishigami N et al. Increased TDP-43 protein in cerebrospinal fluid of patients with amyotrophic lateral sclerosis. Acta Neuropathol;117(1):55-62. 2009-01-01 [PMID: 18989684]
Nishihira Y, Tan CF, Hoshi Y et al. Sporadic amyotrophic lateral sclerosis of long duration is associated with relatively mild TDP-43 pathology. Acta Neuropathol. 2009-01-01 [PMID: 18923836]
Skoglund L, Brundin R, Olofsson T et al. Frontotemporal dementia in a large Swedish family is caused by a progranulin null mutation. Neurogenetics. 2009-02-01 [PMID: 18855025]
Miklossy J, Steele JC, Yu S et al. Enduring involvement of tau, beta-amyloid, alpha-synuclein, ubiquitin and TDP-43 pathology in the amyotrophic lateral sclerosis/parkinsonism-dementia complex of Guam (ALS/PDC). Acta Neuropathol. 2008-12-01 [PMID: 18843496]
Kovacs GG, Majtenyi K, Spina S et al. White Matter Tauopathy With Globular Glial Inclusions: A Distinct Sporadic Frontotemporal Lobar Degeneration. J Neuropathol Exp Neurol. 2008-10-01 [PMID: 18800011]
Weihl CC, Temiz P, Miller SE et al. TDP-43 accumulation in inclusion body myopathy muscle suggests a common pathogenic mechanism with frontotemporal dementia. J Neurol Neurosurg Psychiatry;79(10):1186-9. 2008-10-01 [PMID: 18796596]
Lin WL, Dickson DW. Ultrastructural localization of TDP-43 in filamentous neuronal inclusions in various neurodegenerative diseases. Acta Neuropathol;116(2):205-13. 2008-08-01 [PMID: 18607609]
Mori F, Tanji K, Zhang HX et al. Maturation process of TDP-43-positive neuronal cytoplasmic inclusions in amyotrophic lateral sclerosis with without dementia. Acta Neuropathol;116(2):193-203. 2008-08-01 [PMID: 18560845]
Sleegers K, Kumar-Singh S, Cruts M, Van Broeckhoven C. Molecular pathogenesis of frontotemporal lobar degeneration: basic science seminar in neurology. Arch Neurol. 2009-01-01 [PMID: 18541789]
Igaz LM, Kwong LK, Xu Y et al. Enrichment of C-Terminal Fragments in TAR DNA-Binding Protein-43 Cytoplasmic Inclusions in Brain but not in Spinal Cord of Frontotemporal Lobar Degeneration Amyotrophic Lateral Sclerosis. Am J Pathol;173(1):182-94. 2008-07-01 [PMID: 18535185]
Foulds P, McAuley E, Gibbons L et al. TDP-43 protein in plasma may index TDP-43 brain pathology in Alzheimer's disease frontotemporal lobar degeneration. Acta Neuropathol;116(2):141-6. 2008-08-01 [PMID: 18506455]
Johnson BS, McCaffery JM, Lindquist S et al. A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity. Proc Natl Acad Sci U S A 2008-04-29 [PMID: 18434538]
Winton MJ, Igaz LM, Wong MM et al. Disturbance of nuclear cytoplasmic Tar DNA binding protein (TDP-43) induces disease-like redistribution, sequestration aggregate formation. J Biol Chem;283(19):13302-9. 2008-05-09 [PMID: 18305110]
Zhang HX, Tanji K, Mori F et al. Epitope mapping of 2E2-D3, a monoclonal antibody directed against human TDP-43. Neurosci Lett;434(2):170-4. 2008-03-28 [PMID: 18304732]
Beck J, Rohrer JD, Campbell T et al. A distinct clinical, neuropsychological radiological phenotype is associated with progranulin gene mutations in a large UK series. Brain;131(Pt 3):706-20. 2008-03-01 [PMID: 18234697]
Sanelli T, Xiao S, Horne P et al. Evidence That TDP-43 is Not the Major Ubiquitinated Target Within the Pathological Inclusions of Amyotrophic Lateral Sclerosis. J Neuropathol Exp Neurol. 2007-12-01 [PMID: 18090923]
Kovacs GG, Pittman A, Revesz T et al. MAPT S305I mutation: implications for argyrophilic grain disease. Acta Neuropathol;116(1):103-18. 2008-07-01 [PMID: 18066559]
Shankaran SS, Capell A, Hruscha AT et al. FTLD-U linked missense mutations in the progranulin gene reduce progranulin production and secretion. J. Biol. Chem. 2008-01-18 [PMID: 17984093]
Zhang H, Tan CF, Mori F et al. TDP-43-immunoreactive neuronal glial inclusions in the neostriatum in amyotrophic lateral sclerosis with without dementia. Acta Neuropathol;115(1):115-22. 2008-01-01 [PMID: 17786458]
1 Amador-Ortiz C, Lin WL, Ahmed Z et al. TDP-43 immunoreactivity in hippocampal sclerosis Alzheimer's disease. Ann Neurol;61(5):435-45. 2007-05-01 [PMID: 17469117]
Mackenzie IR, Bigio EH, Ince PG et al. Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Ann Neurol;61(5):427-34. 2007-05-01 [PMID: 17469116]
Hasegawa M, Arai T, Akiyama H et al. TDP-43 is deposited in the Guam parkinsonism-dementia complex brains. Brain;130(Pt 5):1386-94. 2007-05-01 [PMID: 17439983]
Fukuda T, Yamagata K, Fujiyama S et al. DEAD-box RNA helicase subunits of the Drosha complex are required for processing of rRNA and a subset of microRNAs. Nat Cell Biol 2007-05-01 [PMID: 17435748]
Neumann M, Kwong LK, Truax AC et al. TDP-43-positive white matter pathology in frontotemporal lobar degeneration with ubiquitin-positive inclusions. J Neuropathol Exp Neurol;66(3):177-83. 2007-03-01 [PMID: 17356379]
Tan CF, Eguchi H, Tagawa A et al. TDP-43 immunoreactivity in neuronal inclusions in familial amyotrophic lateral sclerosis with or without SOD1 gene mutation. Acta Neuropathol (Berl);113(5):535-42. 2007-05-01 [PMID: 17333220]
Neumann M, Mackenzie IR, Cairns NJ et al. TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations. J Neuropathol Exp Neurol;66(2):152-7. 2007-02-01 [PMID: 17279000]
Arai T, Oda T et al. TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration amyotrophic lateral sclerosis. Biochem Biophys Res Commun;351(3):602-11. 2006-12-22 [PMID: 17084815]
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Images	Ratings	Applications	Species	Date	Details
	5 reviewed by: Verified Customer	WB	Human	01/20/2022	View Summary Application Western Blot Sample Tested 293T cell line Species Human Lot 2E2-D3
Enlarge	5 reviewed by: Verified Customer	IHC-P		10/02/2012	View Summary Application Immunohistochemistry-Paraffin
Enlarge	5 reviewed by: Helen Chiang	WB	Mouse	06/28/2012	View Summary Application Western Blot Sample Tested Mouse Brain Tissue Species Mouse Lot 12076-S1

Array H00023435-M01

• TDP-43/TARDBP Antibodies
• TDP-43/TARDBP ELISA Kits
• TDP-43/TARDBP Lysate
• TDP-43/TARDBP Proteins
• TDP-43/TARDBP Proteins and Enzyme