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Optineurin Antibody [DyLight 550]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 550

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP3-00298AF350
Alexa Fluor 405
NBP3-00298AF405
Alexa Fluor 488
NBP3-00298AF488
Alexa Fluor 532
NBP3-00298AF532
Alexa Fluor 594
NBP3-00298AF594
Alexa Fluor 647
NBP3-00298AF647
Alexa Fluor 700
NBP3-00298AF700
Alexa Fluor 750
NBP3-00298AF750
Allophycocyanin
NBP3-00298APC
Biotin
NBP3-00298B
CoraFluor 1
NBP3-00298CL1
DyLight 350
NBP3-00298UV
DyLight 405
NBP3-00298V
DyLight 488
NBP3-00298G
DyLight 594
NBP3-00298DL594
DyLight 650
NBP3-00298C
DyLight 680
NBP3-00298FR
DyLight 755
NBP3-00298IR
FITC
NBP3-00298F
HRP
NBP3-00298H
Janelia Fluor 525
NBP3-00298JF525
Janelia Fluor 549
NBP3-00298JF549
Janelia Fluor 646
NBP3-00298JF646
Janelia Fluor 669
NBP3-00298JF669
PE
NBP3-00298PE
PerCP
NBP3-00298PCP
Unconjugated
NBP3-00298-100ul
mFluor Violet 450 SE
NBP3-00298MFV450
mFluor Violet 500 SE
NBP3-00298MFV500
mFluor Violet 610 SE
NBP3-00298MFV610
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Optineurin Antibody [DyLight 550] Summary

Immunogen
Produced in rabbits immunized with purified, recombinant Human Optineurin (Accession#: NP_068815.2; Met1-Ile577)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
OPTN
Purity
Antigen and protein A Affinity-purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Optineurin Antibody [DyLight 550]

  • ALS12
  • FIP2
  • FIP2FIP-2
  • GLC1E
  • GLC1Eglaucoma 1, open angle, E (adult-onset)
  • HIP7
  • HIP7ALS12
  • Huntingtin interacting protein L
  • Huntingtin yeast partner L
  • Huntingtin-interacting protein 7
  • Huntingtin-interacting protein L
  • HYPL
  • HYPLHIP-7
  • NEMO-related protein
  • NRP
  • NRPE3-14.7K-interacting protein
  • Optic neuropathy-inducing protein
  • Optineurin
  • OPTN
  • TFIIIA-INTP
  • Transcription factor IIIA-interacting protein
  • transcrption factor IIIA-interacting protein
  • tumor necrosis factor alpha-inducible cellular protein containing leucinezipper domains

Background

Optineurin encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Optineurin
Antibody [DyLight 550
NBP3-00298R
Optineurin Antibody [DyLight 550]
Species: Hu
Applications: WB, ELISA, IP

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Bioinformatics

Gene Symbol OPTN