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NOSTRIN Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: NOSTRIN Antibody [NBP2-13667] - Staining of human cell line A-431 shows localization to nuclear speckles.
Immunohistochemistry-Paraffin: NOSTRIN Antibody [NBP2-13667] - Staining of human salivary gland shows cytoplasmic and membranous positivity in glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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NOSTRIN Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the amino acids: TLENCYQSILELEKERIQLLCNNLNQYSQHISLFGQTLTTCHTQIHCAISKIDIEKDIQAVMEETAILSTENKSEFLLTDYFEEDPNSAMDKERRKSLLKPKLLRL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NOSTRIN
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation/Permeabilization: PFA/Triton X-100.
Control Peptide
NOSTRIN Protein (NBP2-13667PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (89%), Rat (86%)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for NOSTRIN Antibody

  • BM247 homolog
  • DaIP2
  • endothelial nitric oxide synthase traffic inducer
  • ENOS traffic inducer
  • eNOS-trafficking inducer
  • Nitric oxide synthase traffic inducer
  • nitric oxide synthase traffickerMGC20702
  • nitric oxide synthase trafficking
  • nostrin
  • ortholog of mouse disabled 2 interacting proein 2

Background

Nitric oxide (NO) is a potent mediator in biologic processes such as neurotransmission, inflammatory response, and vascular homeostasis. NOSTRIN binds the enzyme responsible for NO production, endothelial NO synthase (ENOS; MIM 163729), and triggers the translocation of ENOS from the plasma membrane to vesicle-like subcellular structures, thereby attenuating ENOS-dependent NO production.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol NOSTRIN