NOD1 Antibody

Nod1 is implicated in the intracellular detection of pathogen associated molecule, such as, microbial peptidoglycans and signals the activation of NF-kB. Nod1 has an NH2-terminal CARD-linked to a nucleotide-binding domain and a COOH-terminal segment with multiple leucine-rich repeats, which are involved in binding to multiple caspases with long prodomains, but specifically activated caspase-9 and promoted caspase-9-induced apoptosis. Nod1 is a leucine-rich repeat-containing Apaf-1-like molecule that can regulate both apoptosis and NF-kB activation pathways.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 3 applications: IF/IHC, KO, WB.

Showing Publications 1 - 4 of 4.

Publications using NB100-56878	Applications	Species
Caputa G, Matsushita M, Sanin DE et al. Intracellular infection and immune system cues rewire adipocytes to acquire immune function Cell metabolism 2022-05-03 [PMID: 35508110] (KO, WB, Mouse)	KO, WB	Mouse
Xiang C, Chen P, Zhang Q et al. Intestinal microbiota modulates adrenomedullary response through Nod1 sensing in chromaffin cells iScience 2021-08-01 [PMID: 34381974]
Ahn M Y, Kang J K et al. Expression of nucleotide-binding oligomerization domain 1 and 2 in oral lichen planus. J Dent Sci 2020-01-03 [PMID: 32256993] (IF/IHC, Human)	IF/IHC	Human
Scott MJ, Chen C, Sun Q, Billiar TR. Hepatocytes express functional NOD1 and NOD2 receptors: a role for NOD1 in hepatocyte CC and CXC chemokine production. J Hepatol. 2010-10-01 [PMID: 20615568] (WB, Mouse) Details: Products cited: NOD1/CARD4 (IMG-5224A) and NOD2/CARD15 (IMG-5738). WB: Mouse C57BL/6 hepatocyte NOD1 & NOD2 siRNA transfected cell line, Fig 4C. Note: The NOD1 (IMG-5224A) and NOD2 (IMG-5738) antibodies were siRNA validated by WB in mouse C57BL/6 hepatocy	WB	Mouse

Array NB100-56878

• NOD1 Antibodies
• NOD1 Lysate
• NOD1 Proteins