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NLRP11 Antibody - Azide and BSA Free

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Western Blot: NLRP11 Antibody [NBP2-93812] - Analysis of extracts of 293T cells, using NLRP11 at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
Azide and BSA Free

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NLRP11 Antibody - Azide and BSA Free Summary

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 420-600 of human NLRP11 (NP_659444.2). VGFTEADVSVLQAANILLPSNTHKDRYKFIHLNVQEFCTAIAFLMAVPNYLIPSGSREYKEKREQYSDFNQVFTFIFGLLNANRRKILETSFGYQLPMVDSFKWYSVGYMKHLDRDPEKLTHHMPLFYCLYENREEEFVKTIVDALMEVTVYLQSDKDMMVSLYCLDYCCHLRTLKLSVQR
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
NLRP11
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol
Preservative
0.01% Thimerosal
Purity
Affinity purified

Alternate Names for NLRP11 Antibody - Azide and BSA Free

  • CLR19.6
  • NACHT, leucine rich repeat and PYD containing 11
  • NALP11NACHT, LRR and PYD domains-containing protein 11
  • NLR family, pyrin domain containing 11
  • NOD17PYPAF7
  • Nucleotide-binding oligomerization domain protein 17
  • nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domaincontaining 11
  • PAAD- and NACHT-containing protein 10
  • PAAD- and NACHT-containing protein 10B
  • PAAD-and NACHT domain-containing protein 10
  • PAN10FLJ26273
  • PYPAF6NACHT, LRR and PYD containing protein 11
  • PYRIN-containing APAF1-like protein 6

Background

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including Methotrexate, which is known to the State of California to cause reproductive toxicity with developmental effects. For more information, go to www.P65Warnings.ca.gov

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Secondary Antibodies

 

Isotype Controls

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Research Areas for NLRP11 Antibody (NBP2-93812)

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Blogs on NLRP11.

The NLRP3 Inflammasome: Macrophage Activator & Pathology Driver
By Victoria Osinski, PhDWhat is the NLRP3 Inflammasome?With its critical role in innate immunity, the nucleotide-binding oligomerization domain-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome ...  Read full blog post.

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Bioinformatics

Gene Symbol NLRP11