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Nicotinic Acetylcholine Receptor beta 4 Antibody

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Western Blot: Nicotinic Acetylcholine Receptor beta 4 Antibody [NBP2-60788] - Western blot of mouse habenula lysate showing specificimmunolabeling of the ~52 kDa nAChR-Beta-4 protein.

Product Details

Summary
Reactivity Mu, RtSpecies Glossary
Applications WB, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Nicotinic Acetylcholine Receptor beta 4 Antibody Summary

Immunogen
Fusion protein from the cytoplasmic loop of the beta 4 subunit of rat nAChR. Accession # Q8R493
Specificity
Specific for endogenous levels of the ~52 kDa Nicotinic Acetylcholine Receptor beta 4 protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
CHRNB4
Purity
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 1:10-1:500
  • Western Blot 1:100-1:2000
Theoretical MW
52 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
10 mM HEPES (pH 7.5), 0.15 M NaCl, 0.1 mg/mL BSA, 50% Glycerol
Preservative
No Preservative
Purity
Antigen Affinity-purified

Alternate Names for Nicotinic Acetylcholine Receptor beta 4 Antibody

  • cholinergic receptor, nicotinic, beta 4
  • cholinergic receptor, nicotinic, beta polypeptide 4
  • CHRNB4
  • NAChRB4
  • neuronal acetylcholine receptor subunit beta-4
  • neuronal nicotinic receptor beta 4 subunit
  • Nicotinic Acetylcholine R beta 4

Background

The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The nAChRs are thought to be (hetero) pentamers composed of homologous subunits. After binding acetylcholine, the nAChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Nicotinic Acetylcholine Receptor beta 4 Antibody (NBP2-60788) (0)

There are no publications for Nicotinic Acetylcholine Receptor beta 4 Antibody (NBP2-60788).
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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Nicotinic Acetylcholine Receptor beta 4 Antibody (NBP2-60788). (Showing 1 - 1 of 1 FAQ).

  1. I am looking to buy antibodies against most of the nicotinic receptor subunits for WB and IHC application. Could you please indicate which of your antibodies have been used by other researchers and provide publications showing their use? Thanks.
    • A list of our antibodies directed against he nicotinic acetylcholine receptors can be found here. Any products with publications will be indicated on the search page and can be found under the publications tab on the individual product's datasheet. Furthermore, we guarantee all of our products for the applications and species list on the datasheet. This should help narrow down your search.

Secondary Antibodies

 

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Bioinformatics

Gene Symbol CHRNB4