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NHERF-2 Antibody

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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NHERF-2 Antibody Summary

Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 180-300 of human NHERF-2 (NP_001123484).

Sequence:
DPGSPAARSGLRAQDRLIEVNGQNVEGLRHAEVVASIKAREDEARLLVVDPETDEHFKRLRVTPTEEHVEGPLPSPVTNGTSPAQLNGGSACSSRSDLPGSDKDTEDGSAWKQDPFQESGL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLC9A3R2
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 1:500 - 1:2000
Theoretical MW
37 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol
Preservative
0.01% Thimerosal
Purity
Affinity purified

Alternate Names for NHERF-2 Antibody

  • E3KARP
  • Na(+)/H(+) exchange regulatory cofactor NHE-RF2
  • NHE3RF2
  • NHERF2MGC104639
  • NHERF-2NHE3 kinase A regulatory protein E3KARP
  • OCTS2
  • SIP-1SRY-interacting protein 1
  • sodium/hydrogen exchanger
  • Sodium-hydrogen exchanger regulatory factor 2
  • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulator 2
  • solute carrier family 9 (sodium/hydrogen exchanger), isoform 3 regulatoryfactor 2
  • solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
  • Solute carrier family 9 isoform A3 regulatory factor 2
  • TKA-1SIP1
  • Tyrosine kinase activator protein 1

Background

NHERF-2 is a scaffold protein that connects plasma membrane proteins with members of the ezrin/moesin/radixin family and thereby helps to link them to the actin cytoskeleton and to regulate their surface expression. Necessary for cAMP-mediated phosphorylation and inhibition of SLC9A3. May also act as scaffold protein in the nucleus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SLC9A3R2