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Human Neutrophil Elastase/ELA2 ELISA Kit (Colorimetric)

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ELISA: Human Neutrophil Elastase/ELA2 ELISA Kit (Colorimetric) [NBP2-60501] - Standard Curve.
ELISA: Human Neutrophil Elastase/ELA2 ELISA Kit (Colorimetric) [NBP2-60501] - Standard Curve.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Suitable Sample Type
Serum, Plasma, Cell Culture, Urine, Saliva, Milk, CSF
Standard Curve Range
0.078 - 5 ng/mL (example only; lot dependent)
Sensitivity
0.11 ng/ml (example only; lot dependent)

Order Details

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Human Neutrophil Elastase/ELA2 ELISA Kit (Colorimetric) Summary

Description
This assay employs a quantitative enzyme immunoassay technique that measures the specified antigen in samples.
Standard Curve Range
0.078 - 5 ng/mL (example only; lot dependent)
Sensitivity
0.11 ng/ml (example only; lot dependent)
Assay Type
Sandwich ELISA
Inter-Assay
CV% < 9.70% (example only; lot dependent)
Intra-Assay
CV% < 5.00% (example only; lot dependent)
Spike Recovery
97.00% (example only; lot dependent)
Kit Type
ELISA Kit (Colorimetric)
Gene
ELANE

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

Storage
Storage is content dependent.

Alternate Names for Human Neutrophil Elastase/ELA2 ELISA Kit (Colorimetric)

  • Bone marrow serine protease
  • EC 3.4.21
  • EC 3.4.21.37
  • ELA2
  • ELA2granulocyte-derived elastase
  • ELANE
  • elastase 2, neutrophil
  • elastase, neutrophil expressed
  • Elastase-2
  • GE
  • HLEelastase-2
  • HNE
  • Human leukocyte elastase
  • Leukocyte Elastase
  • Medullasin
  • NE
  • Neutrophil Elastase
  • PMN elastase
  • PMN-E
  • polymorphonuclear elastase
  • SCN1

Background

The ELANE gene (commonly known as neutrophil elastase) encodes a 267 amino acid long, 28 kDA neutrophil elastase protein that functions in regulation of natural killer cells, monocytes, and graulocytes. ELANE is involved in activation of proMMP8, cell adhesion cell-matrix glycoconjugates, selected targets of C/EBPbeta, degradation of the extracellular matrix and collagen, and amb2 integrin signaling. It interacts with various genes GZMB, LRP1, SERPINF2, SERPING1, and SERPINA1. Elane has been linked to cystic fibrosis, asthma, pneumonia, alzheimer's disease, neutropenia, cutis laxia, leg ulcers, wegener's granulomatosis, bronchitis, adult respiratory distress syndrome, and vascular diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol ELANE