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Neutrophil Elastase/ELA2 Antibody (950334) [FITC]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, IHC
Clone
950334
Clonality
Monoclonal
Host
Mouse
Conjugate
FITC

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
MAB9167AF350
Alexa Fluor 405
MAB9167AF405
Alexa Fluor 488
MAB9167AF488
Alexa Fluor 532
MAB9167AF532
Alexa Fluor 594
MAB9167AF594
Alexa Fluor 647
MAB9167AF647
Alexa Fluor 700
MAB9167AF700
Alexa Fluor 750
MAB9167AF750
Biotin
MAB9167B
DyLight 350
MAB9167UV
DyLight 405
MAB9167V
DyLight 488
MAB9167G
DyLight 550
MAB9167R
DyLight 594
MAB9167DL594
DyLight 650
MAB9167C
DyLight 680
MAB9167FR
DyLight 755
MAB9167IR
HRP
MAB9167H
Janelia Fluor 549
MAB9167JF549
Janelia Fluor 646
MAB9167JF646
PE
MAB9167PE
PerCP
MAB9167PCP
Unconjugated
MAB9167
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB9167
Azide and BSA Free
MAB9167
Azide and BSA Free
MAB9167-SP
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Neutrophil Elastase/ELA2 Antibody (950334) [FITC] Summary

Description
>90% by SDS PAGE
Immunogen
Partial recombinant human ELA2 protein (aa28-252)
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ELANE
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Alternate Names for Neutrophil Elastase/ELA2 Antibody (950334) [FITC]

  • Bone marrow serine protease
  • EC 3.4.21
  • EC 3.4.21.37
  • ELA2
  • ELA2granulocyte-derived elastase
  • ELANE
  • elastase 2, neutrophil
  • elastase, neutrophil expressed
  • Elastase-2
  • GE
  • HLEelastase-2
  • HNE
  • Human leukocyte elastase
  • Leukocyte Elastase
  • Medullasin
  • NE
  • Neutrophil Elastase
  • PMN elastase
  • PMN-E
  • polymorphonuclear elastase
  • SCN1

Background

The ELANE gene (commonly known as neutrophil elastase) encodes a 267 amino acid long, 28 kDA neutrophil elastase protein that functions in regulation of natural killer cells, monocytes, and graulocytes. ELANE is involved in activation of proMMP8, cell adhesion cell-matrix glycoconjugates, selected targets of C/EBPbeta, degradation of the extracellular matrix and collagen, and amb2 integrin signaling. It interacts with various genes GZMB, LRP1, SERPINF2, SERPING1, and SERPINA1. Elane has been linked to cystic fibrosis, asthma, pneumonia, alzheimer's disease, neutropenia, cutis laxia, leg ulcers, wegener's granulomatosis, bronchitis, adult respiratory distress syndrome, and vascular diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ELANE