Home » Neutrophil Elastase/ELA2 » Neutrophil Elastase/ELA2 Antibodies » Neutrophil Elastase/ELA2 Antibody (950317) [mFluor Violet 610 SE]

Neutrophil Elastase/ELA2 Antibody (950317) [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, CyTOF-ready, Flow, ICC/IF
Clone
950317
Clonality
Monoclonal
Host
Mouse
Conjugate
mFluor Violet 610 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC91671U-100UG
Alexa Fluor 405
IC91671V-100UG
Alexa Fluor 488
IC91671G-100UG
Alexa Fluor 532
FAB91671X
Alexa Fluor 594
IC91671T-100UG
Alexa Fluor 647
IC91671R-100UG
Alexa Fluor 700
IC91671N-100UG
Alexa Fluor 750
IC91671S-100UG
Allophycocyanin
FAB91671A
Biotin
FAB91671B
CoraFluor 1
FAB91671CL1
DyLight 350
FAB91671D
DyLight 405
FAB91671E
DyLight 488
FAB91671K
DyLight 550
FAB91671L
DyLight 594
FAB91671M
DyLight 650
FAB91671W
DyLight 680
FAB91671Y
DyLight 755
FAB91671Z
FITC
FAB91671F
HRP
FAB91671H
Janelia Fluor 525
FAB91671JF525
Janelia Fluor 549
FAB91671I
Janelia Fluor 646
FAB91671J
Janelia Fluor 669
FAB91671JF669
PE
FAB91671P
PerCP
FAB91671C
Unconjugated
MAB91671-100
mFluor Violet 450 SE
FAB91671MFV450
mFluor Violet 500 SE
FAB91671MFV500
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB91671-100
Carrier Free
MAB91671-100
Carrier Free
MAB91671-SP
Carrier Free
IC91671V-100UG
Carrier Free
IC91671U-100UG
Carrier Free
IC91671T-100UG
Carrier Free
IC91671S-100UG
Carrier Free
IC91671R-100UG
Carrier Free
IC91671N-100UG
Carrier Free
IC91671G-100UG
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Neutrophil Elastase/ELA2 Antibody (950317) [mFluor Violet 610 SE] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human ELA2
Met1-Asn252
Accession # P08246
Specificity
Detects human ELA2 in direct ELISAs and Western blots.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Immunocytochemistry
  • Immunohistochemistry
  • Intracellular Staining by Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Neutrophil Elastase/ELA2 Antibody (950317) [mFluor Violet 610 SE]

  • Bone marrow serine protease
  • EC 3.4.21
  • EC 3.4.21.37
  • ELA2
  • ELA2granulocyte-derived elastase
  • ELANE
  • elastase 2, neutrophil
  • elastase, neutrophil expressed
  • Elastase-2
  • GE
  • HLEelastase-2
  • HNE
  • Human leukocyte elastase
  • Leukocyte Elastase
  • Medullasin
  • NE
  • Neutrophil Elastase
  • PMN elastase
  • PMN-E
  • polymorphonuclear elastase
  • SCN1

Background

The ELANE gene (commonly known as neutrophil elastase) encodes a 267 amino acid long, 28 kDA neutrophil elastase protein that functions in regulation of natural killer cells, monocytes, and graulocytes. ELANE is involved in activation of proMMP8, cell adhesion cell-matrix glycoconjugates, selected targets of C/EBPbeta, degradation of the extracellular matrix and collagen, and amb2 integrin signaling. It interacts with various genes GZMB, LRP1, SERPINF2, SERPING1, and SERPINA1. Elane has been linked to cystic fibrosis, asthma, pneumonia, alzheimer's disease, neutropenia, cutis laxia, leg ulcers, wegener's granulomatosis, bronchitis, adult respiratory distress syndrome, and vascular diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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