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n-Myc Antibody (NMYC-1) [Janelia Fluor® 585]

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Summary
Product Discontinued
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    • Catalog Number
      NBP3-08495JF585
    • Availability
      Product Discontinued

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n-Myc Antibody (NMYC-1) [Janelia Fluor® 585] Summary

Immunogen
Recombinant full-length human n-Myc protein. (Uniprot: P04198)
Localization
Nucleus.
Marker
Neuroblastoma Marker
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MYCN
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for n-Myc Antibody (NMYC-1) [Janelia Fluor® 585]

  • BHLHE37
  • bHLHe37N-myc proto-oncogene protein
  • Class E basic helix-loop-helix protein 37
  • MODED
  • neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene
  • N-myc
  • NMYCneuroblastoma MYC oncogene
  • ODED
  • oncogene NMYC
  • pp65/67
  • v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)

Background

n-Myc is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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n-Myc Antibody
(NMYC-1) [Janelia Flu ...
NBP3-08495JF585
n-Myc Antibody (NMYC-1) [Janelia Fluor® 585]
Species: Hu, Mu, Rt
Applications: WB, ICC/IF

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Product General Protocols

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Video Protocols

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ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Research Areas for n-Myc Antibody (NBP3-08495JF585)

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Blogs on n-Myc.

Check out the latest blog posts on n-Myc.
Dual applications of a c-Myc antibody in mitochondrial research
c-Myc, a proto-oncogene, has documented involvement in cellular differentiation, cell growth, cell death and tumor formation.  Target genes of the Myc family include those that participate in cell survival, translation, transcription, metabolism and...  Read full blog post.
Read our latest blog and use the new citation tool on bio-techne.com

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Bioinformatics

Gene Symbol MYCN