MST1/2 Antibody Summary
Immunogen |
The immunogen this antibody was made to, maps to the C-terminus of human Mammalian Sterile 20-like 2 (Serine/Threonine Kinase 3) using the numbering given in Swiss Prot entry Q13188 (GeneID 6788). The epitope is highly conserved with MST1(STK4). |
Predicted Species |
Mouse (100%), Rat (100%), Monkey (100%), Xenopus (100%), Turkey (100%), Equine (100%), Zebrafish (100%), Bovine (100%), Orangutan (100%), Guinea Pig (100%), Rabbit (100%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
STK3 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry 1:100 - 1:500
- Immunohistochemistry-Paraffin 1:100-1:500
|
Application Notes |
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining. |
Packaging, Storage & Formulations
Storage |
Store at 4C. Do not freeze. |
Buffer |
TBS and 0.1% BSA |
Preservative |
0.09% Sodium Azide |
Concentration |
0.25 mg/ml |
Purity |
Immunogen affinity purified |
Alternate Names for MST1/2 Antibody
Background
MST1 and MST2 are members of the sterile 20 (Ste20)-like kinase family that acts upstream of mitogen-activated protein kinase (MAPK) pathways and regulates c-Jun N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK). Ste20-like kinases are involved in a variety of cellular processes which include gene transcription, stress responses, cytoskeletal organization and apoptosis. In response to apoptotic signals, MST1 and MST2 are cleaved by caspase-3 and mediate apoptosis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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