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MST1/2 Antibody

Images

 
Immunohistochemistry-Paraffin: MST1/2 Antibody [NBP1-28672] - Section of human colon carcinoma. Antibody: Affinity purified rabbit antiMST1,2/STK3,4 used at a dilution of 1:250. Detection: DAB
Immunohistochemistry-Paraffin: MST1/2 Antibody [NBP1-28672] - Section of human placenta. Antibody: Affinity purified rabbit antiMST1,2/STK3,4 used at a dilution of 1:250. Detection: DAB

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Eq, Gp, Pm, Pm-Or, Rb, Tr, Xp, ZeSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.25 mg/ml

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MST1/2 Antibody Summary

Immunogen
The immunogen this antibody was made to, maps to the C-terminus of human Mammalian Sterile 20-like 2 (Serine/Threonine Kinase 3) using the numbering given in Swiss Prot entry Q13188 (GeneID 6788). The epitope is highly conserved with MST1(STK4).
Predicted Species
Mouse (100%), Rat (100%), Monkey (100%), Xenopus (100%), Turkey (100%), Equine (100%), Zebrafish (100%), Bovine (100%), Orangutan (100%), Guinea Pig (100%), Rabbit (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
STK3
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:100 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:500
Application Notes
Epitope exposure with tris-EDTA pH9.0 buffer will enhance staining.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.25 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MST1/2 Antibody

  • KRS1
  • KRS2
  • Mammalian STE20-like protein kinase 1
  • Mammalian STE20-like protein kinase 2
  • mammalian sterile 20-like 1
  • serine/threonine-protein kinase 3
  • serine/threonine-protein kinase 4
  • Serine/threonine-protein kinase Krs-1
  • YSK3

Background

MST1 and MST2 are members of the sterile 20 (Ste20)-like kinase family that acts upstream of mitogen-activated protein kinase (MAPK) pathways and regulates c-Jun N-terminal kinase (JNK), p38 and extracellular signal-regulated kinase (ERK). Ste20-like kinases are involved in a variety of cellular processes which include gene transcription, stress responses, cytoskeletal organization and apoptosis. In response to apoptotic signals, MST1 and MST2 are cleaved by caspase-3 and mediate apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol STK3
Entrez
Uniprot