![Western Blot: MRP1 Antibody (IU5C1) [NB110-57131] - Detection of MRP1 in 10 ug of 293 transfected (lane 2) and empty vector (lane 1) lysate.](http://images.novusbio.com/fullsize/MRP1-Antibody-IU5C1-Western-Blot-NB110-57131-img0002.jpg "Western Blot: MRP1 Antibody (IU5C1) [NB110-57131] - Detection of MRP1 in 10 ug of 293 transfected (lane 2) and empty vector (lane 1) lysate.")
| Reactivity | Hu, Mu, Rt, Fe, PmSpecies Glossary |
| Applications | WB, ICC/IF, IHC |
| Clone | IU5C1 |
| Clonality | Monoclonal |
| Host | Mouse |
| Conjugate | Unconjugated |
| Format | BSA Free |
| Concentration | 1.0 mg/ml |
| Immunogen | A recombinant peptide corresponding to residues 1-33 (N-terminal: SMALRGFCSADGSDPLWDWNVTWNTSNPDFTKCF) of human MRP1. [Swiss-Prot# P33527] |
| Epitope | Residues 14-19 (PLWDWN) of the human protein. |
| Predicted Species | Rat (96%), Primate (96%), Feline (96%). Backed by our 100% Guarantee. |
| Isotype | IgG1 |
| Clonality | Monoclonal |
| Host | Mouse |
| Gene | ABCC1 |
| Purity | Protein G purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
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| Application Notes | This MRP1 antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot analysis on transfected lysate, where a band is seen at ~172 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Theoretical MW | 172 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Storage | Store at -20C. Avoid freeze-thaw cycles. |
| Buffer | PBS |
| Preservative | 0.1% Sodium Azide |
| Concentration | 1.0 mg/ml |
| Purity | Protein G purified |
| Publication using NB110-57131 | Applications | Species |
|---|---|---|
| Chen Q, Yang Y, Li L, Zhang JT. The amino terminus of the human multidrug resistance transporter ABCC1 has a U-shaped folding with a gating function. J Biol Chem;281(41):31152-63. 2006-10-13 [PMID: 16914551] (ICC/IF, Human) | ICC/IF | Human |
Secondary Antibodies |
Isotype Controls |
Research Areas for MRP1 Antibody (NB110-57131)Find related products by research area.
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ABC Membrane transporters and the role of MRP1 in drug resistance ATP-binding cassette (ABC) transporters, alongside ion channels and aquaporins, are ubiquitous membrane-bound proteins that move substrates across extra and intra cellular membranes. Multidrug resistance-associated protein 1 (MRP1) is a member o... Read full blog post. |
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![Immunocytochemistry/Immunofluorescence: MRP1 Antibody (IU5C1) [NB110-57131] - Staining of MRP1 using NB110-57131 in HEK293 cells with MRP1 expression.](http://images.novusbio.com/fullsize/MRP1-Antibody-IU5C1-Immunocytochemistry-Immunofluorescence-NB110-57131-img0006.jpg "Immunocytochemistry/Immunofluorescence: MRP1 Antibody (IU5C1) [NB110-57131] - Staining of MRP1 using NB110-57131 in HEK293 cells with MRP1 expression.")
![Immunohistochemistry-Paraffin: MRP1 Antibody (IU5C1) [NB110-57131] - Analysis of a FFPE tissue section of mouse testis using 1:200 dilution of MRP1 [IU5C1] antibody. The staining was developed using HRP labeled anti-mouse secondary antibody and DAB reagent, and nuclei of cells were counter-stained with hematoxylin.](http://images.novusbio.com/fullsize/MRP1-Antibody-IU5C1-Immunohistochemistry-Paraffin-NB110-57131-img0007.jpg "Immunohistochemistry-Paraffin: MRP1 Antibody (IU5C1) [NB110-57131] - Analysis of a FFPE tissue section of mouse testis using 1:200 dilution of MRP1 [IU5C1] antibody. The staining was developed using HRP labeled anti-mouse secondary antibody and DAB reagent, and nuclei of cells were counter-stained with hematoxylin.")
![Immunohistochemistry CFTR Antibody (24-1) [Unconjugated] - C-terminus](https://images.novusbio.com/images2/CFTR_MAB25031_Immunohistochemistry_6973.jpg)
![Immunohistochemistry CFTR Antibody (24-1) [Unconjugated] - C-terminus](https://images.novusbio.com/images2/CFTR_MAB25031_Immunohistochemistry_9671.jpg)
![Immunoprecipitation CFTR Antibody (24-1) [Unconjugated] - C-terminus](https://images.novusbio.com/images/mab25031_human-cftr-c-terminus-mab-clone-24-1-41202412513815.jpg)
![SDS-Page: Mouse IgG1 Isotype Control (MG1) [NBP1-97005] - Lane 1: , Non-reduced. M: Opal Pre-stained Ladder. Lane 2: , Reduced. Load: 1.0 ug per lane. Predicted/Observed: 120 kDa Non-reduced, 55 and 25 Reduced.](https://images.novusbio.com/images/Mouse-IgG1-Isotype-Control-MG1-SDS-Page-NBP1-97005-img0002.jpg "SDS-Page: Mouse IgG1 Isotype Control (MG1) [NBP1-97005] - Lane 1: , Non-reduced. M: Opal Pre-stained Ladder. Lane 2: , Reduced. Load: 1.0 ug per lane. Predicted/Observed: 120 kDa Non-reduced, 55 and 25 Reduced.")