Species: Hu, Mu, Rt
Applications: WB, Simple Western, ELISA, Flow, ICC/IF, IHC, IP, CyTOF-ready, Dual ISH-IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Fe, Pm
Applications: WB, ICC/IF, IHC
Host: Mouse Monoclonal
Species: Hu
Applications: WB, IP, CyTOF-ready, Flow, ICC/IF
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Species: Hu
Applications: AC
Description
Multidrug Resistance Protein 1 (MRP1) is an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein. MRP1 is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumours. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump.
Specifically, MRP1 mediates the export of organic anions and drugs from the cytoplasm. It is through this function, that MRP1 is able to confer resistance to anticancer drugs. MRP1 antibodies are therefore useful tools for cancer testing and research.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
|
| Product By Gene ID |
4363 |
| Alternate Names |
- ABC29
- ABCC
- ATP-binding cassette sub-family C member 1
- ATP-binding cassette, sub-family C (CFTR/MRP), member 1
- EC 3.6.3
- EC 3.6.3.44
- GS-X
- Leukotriene C(4) transporter
- LTC4 transporter
- MRP1DKFZp781G125
- MRPDKFZp686N04233
- multidrug resistance associated protein 1
- multidrug resistance protein
- multidrug resistance-associated protein 1
- multiple drug resistance protein 1
- multiple drug resistance-associated protein
|
![Immunocytochemistry MRP1 Antibody (QCRL) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab19291_human-mrp1-mab-clone-qcrl-immunocytochemistry-176202115243.jpg)
