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MRP1 Antibody (IU2H10) - Azide and BSA Free

Images

 
Western Blot: MRP1 Antibody (IU2H10) - Azide and BSA Free [NBP2-80857] - Vector-transfected HEK293 cells 2: MRP1-transfected cells, prep1 3: MRP1-transfected cells, prep2 (the lower band is a degradation product.) Image ...read more
Immunocytochemistry/ Immunofluorescence: MRP1 Antibody (IU2H10) - Azide and BSA Free [NBP2-80857] - The MRP-1 antibody was tested in HeLa cells at a 1:50 dilution against Dylight 488 (Green). Alpha tubulin and nuclei ...read more
Dual RNAscope ISH-IHC: MRP1 Antibody (IU2H10) - Azide and BSA Free [NBP2-80857] - Formalin-fixed paraffin-embedded tissue sections of human testis were probed for MRP1 mRNA (ACD RNAScope Probe, catalog # 435591; Fast ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IP, CyTOF-ready, Dual ISH-IHC
Clone
IU2H10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
Azide and BSA Free
Concentration
1 mg/ml

Order Details

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MRP1 Antibody (IU2H10) - Azide and BSA Free Summary

Immunogen
Recombinant peptide (a.a. 1-33) of human MRP1. [UniProt# P33527].
Epitope
Amino acids 8-17 of human MRP1.
Localization
Membrane
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ABCC1
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Dual RNAscope ISH-IHC
  • ELISA reported in scientific literature
  • Flow Cytometry reported in scientific literature
  • Immunocytochemistry/ Immunofluorescence 1:50-1:200
  • Immunoprecipitation reported in scientific literature
  • Western Blot 1:500
Application Notes
In Western blot a band was observed at ~170-190 kDa in transfected samples. There may be a lower MW band that is a degradation product. This antibody is CyTOF ready.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
No Preservative
Concentration
1 mg/ml
Purity
Protein G purified

Alternate Names for MRP1 Antibody (IU2H10) - Azide and BSA Free

  • ABC29
  • ABCC
  • ABCC1
  • ATP-binding cassette sub-family C member 1
  • ATP-binding cassette, sub-family C (CFTR/MRP), member 1
  • EC 3.6.3
  • EC 3.6.3.44
  • GS-X
  • Leukotriene C(4) transporter
  • LTC4 transporter
  • MRP1
  • MRP1DKFZp781G125
  • MRPDKFZp686N04233
  • multidrug resistance associated protein 1
  • multidrug resistance protein
  • multidrug resistance-associated protein 1
  • multiple drug resistance protein 1
  • multiple drug resistance-associated protein

Background

The MRP molecule, an integral membrane glycophosphoprotein belonging to the same superfamily of ATP-binding cassette transmembrane transporter proteins as P-glycoprotein, is overexpressed in many P-glycoprotein-negative, multidrug resistant cell lines and tumours. It is believed that the main function of MRP in drug resistance is that of a plasma membrane drug efflux pump.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MRP1 Antibody (NBP2-80857) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for MRP1 Antibody (NBP2-80857) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for MRP1 Antibody (NBP2-80857)

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Blogs on MRP1.

ABC Membrane transporters and the role of MRP1 in drug resistance
ATP-binding cassette (ABC) transporters, alongside ion channels and aquaporins, are ubiquitous membrane-bound proteins that move substrates across extra and intra cellular membranes.  Multidrug resistance-associated protein 1 (MRP1) is a member o...  Read full blog post.

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Bioinformatics

Gene Symbol ABCC1