Reactivity | Hu, Mu, RtSpecies Glossary |
Applications | WB |
Clone | 448406 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | Unconjugated |
Concentration | LYOPH |
Immunogen | E. coli-derived recombinant human MP1 Ala2-Ser124 Accession # Q9UHA4 |
Specificity | Detects human, mouse, and rat MP1 in Western blots. |
Source | N/A |
Isotype | IgG2b |
Clonality | Monoclonal |
Host | Mouse |
Gene | LAMTOR3 |
Purity Statement | Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative | No Preservative |
Concentration | LYOPH |
Reconstitution Instructions | Reconstitute at 0.5 mg/mL in sterile PBS. |
MP1 (MEK Partner 1), gene name LAMTOR3 (late endosomal/lysosomal adaptor and MAPK and MTOR activator 3), was initially identified as a scaffold protein that tethers MEK1 and ERK1 to facilitate their activation. MP1 and other MAPK scaffolds promote phosphorylation efficiency and specificity, localize their bound pathway components to particular subcellular sites, and serve as nodes of signal integration for regulation of MAPK pathways by other signaling events. With the assistance of adaptor protein p14, the bound MP1 complex localizes to late endosomes and is thought to regulate endosomal traffic and cellular proliferation during tissue homeostasis.
Secondary Antibodies |
Isotype Controls |
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