Novus Biologicals products are now on bio-techne.com

Mouse TSLPR DuoSet ELISA, 15 Plate

Images

 

Product Details

Summary
Reactivity MuSpecies Glossary
Applications ELISA
Conjugate
Biotin

Order Details

Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Mouse TSLPR DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Crlf2

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Mouse TSLPR DuoSet ELISA, 15 Plate

  • CRL2
  • CRL2cytokine receptor CRL2 precusor
  • CRLF2
  • CRLF2Y
  • CRLM-2
  • Cytokine receptor-like 2
  • cytokine receptor-like factor 2
  • ILXR
  • IL-XR
  • P2RY8/CRLF2 fusion
  • PCOR1
  • Thymic stromal lymphopoietin protein receptor
  • thymic stromal lymphopoietin receptor
  • thymic stromal-derived lymphopoietin receptor
  • TSLP R
  • TSLP receptor
  • TSLPR

Background

Thymic Stromal Lymphopoietin (TSLP) was originally identified as an activity from the conditioned medium of a mouse thymic stromal cell line that promoted the development of B cells. The activities of mouse TSLP overlap with, but are distinct from, those of mouse IL-7. Both mouse TSLP and IL-7 can co-stimulate growth of thymocytes and mature T cells, and support B lymphopoiesis in long-term cultures of fetal liver cells and bone-marrow cells. Whereas mouse IL-7 facilitates the development of B220+/IgM- pre-B cells, mouse TSLP promotes the development B220+/IgM+ B cells. Human TSLP was reported to preferentially stimulate myeloid cells, inducing the release of T cell-attracting chemokines from monocytes and enhancing the maturation of CD11c+ dendritic cells. Human TSLP cDNA encodes a 159 amino acid (aa) residue precursor protein with a 28 aa signal sequence. Within the mature region, six of the seven cysteine residues present in the mouse TSLP involved in intramolecular disulfide bond formation are conserved in the human TSLP. Human TSLP shares approximately 43% aa sequence identity with mouse TSLP. By Northern blot analysis, human TSLP expression has been detected in many tissues with the highest expressions in heart, liver, testis and prostate. TSLP signals through a heterodimeric receptor complex that consists of IL-7 R alpha and the TSLP R, a member of the hemopoietin receptor family most closely related to Rgammac.

TSLP R, also named Delta and CRLM-2 (Cytokine Receptor-like Module-2), was originally cloned as a novel type 1 cytokine receptor with similarity to the common gamma chain (gamma c). It was subsequently identified as a subunit of the cellular receptor for the IL-7-like cytokine TSLP and termed TSLP R. TSLP R shows 24% sequence identity with the mouse gc receptor. TSLP R expression is constitutive in immune and hematopoietic cells, but is up-regulated in Th2 cells.

Customers Who Viewed This Item Also Viewed...

1398-TS/CF
Species: Hu
Applications: BA
207-IL
Species: Hu
Applications: BA
NBP2-59451
Species: Hu
Applications: ELISA, Flow, ICC/IF, MiAr, WB
6507-IL/CF
Species: Hu
Applications: BA
NBP1-19371
Species: Ca, Hu, Mu, Po, Rb, Rt
Applications: Dual ISH-IHC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, Simple Western, WB
AF2168
Species: Hu, Mu
Applications: ChIP, Simple Western, WB
AF1584
Species: Hu, Mu
Applications: CyTOF-ready, ICC, IP, ICFlow, KO, Simple Western, WB
AF4984
Species: Hu
Applications: ChIP, CyTOF-ready, ICC, ICFlow, Simple Western, WB
DY413
Species: Mu
Applications: ELISA
MAB4260
Species: Hu, Mu, Rt
Applications: CyTOF-ready, ICC, IHC, ICFlow, Simple Western, WB
NBP1-72042
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, PEP-ELISA, WB
AF284
Species: Hu
Applications: CyTOF-ready, Flow, Neut, WB
DDX0700P-100
Species: Ca, Hu
Applications: B/N, Flow, IP
202-IL
Species: Hu
Applications: BA
MAB10541
Species: Hu
Applications: CyTOF-ready, Flow, ICC, Neut
DY417
Species: Mu
Applications: ELISA
DY546
Species: Mu
Applications: ELISA

Publications for TSLPR/CRLF2 (DY546) (0)

There are no publications for TSLPR/CRLF2 (DY546).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for TSLPR/CRLF2 (DY546) (0)

There are no reviews for TSLPR/CRLF2 (DY546). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for TSLPR/CRLF2 (DY546) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Additional TSLPR/CRLF2 Products

Blogs on TSLPR/CRLF2

There are no specific blogs for TSLPR/CRLF2, but you can read our latest blog posts.
Read our latest blog and use the new citation tool on bio-techne.com

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Review this Product

Be the first to review our Mouse TSLPR DuoSet ELISA, 15 Plate and receive a gift card or discount.

Bioinformatics

Gene Symbol Crlf2