Mouse E-Selectin/CD62E DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The Selectin family is comprised of three members, E-Selectin, L-Selectin, and P-Selectin. E-Selectin [endothelial leukocyte adhesion molecule-1 (ELAM-1), CD62E] is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. The human and rat proteins share approximately 67% amino acid sequence identity. The mouse and rat proteins share approximately 78% amino acid sequence identity. L-Selectin (Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is expressed constitutively on a wide variety of leukocytes. Two forms of L-Selectin have been reported, apparently arising as a result of post-translational modifications. Human and mouse L-Selectin share 76% amino acid sequence identity. Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P) is expressed by activated platelets and endothelial cells. The extracellular domains of human and mouse P-Selectin share approximately 73% amino acid sequence identity.

We have publications tested in 1 confirmed species: Mouse.

Showing Publications 1 - 7 of 7.

Publications using DY575	Applications	Species
F Seidel, R Kleemann, W van Duyven, N van Trigt, N Keijzer, S van der Ko, C van Kooten, L Verschuren, A Menke, AJ Kiliaan, J Winter, TR Hughes, BP Morgan, F Baas, K Fluiter, MC Morrison Therapeutic Intervention with Anti-Complement Component 5 Antibody Does Not Reduce NASH but Does Attenuate Atherosclerosis and MIF Concentrations in Ldlr-/-.Leiden Mice International Journal of Molecular Sciences, 2022-09-14;23(18):. 2022-09-14 [PMID: 36142647] (Mouse)		Mouse
D Shah, P Das, S Acharya, B Agarwal, DJ Christense, SM Robertson, V Bhandari Small Immunomodulatory Molecules as Potential Therapeutics in Experimental Murine Models of Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS) International Journal of Molecular Sciences, 2021-03-04;22(5):. 2021-03-04 [PMID: 33806560] (Mouse)		Mouse
KJ Kim, SH Kwon, JH Yun, HS Jeong, HR Kim, EH Lee, SK Ye, CH Cho STAT3 activation in endothelial cells is important for tumor metastasis via increased cell adhesion molecule expression Oncogene, 2017-05-22;0(0):. 2017-05-22 [PMID: 28534515] (Mouse)		Mouse
Shih M, Cherng J Reduction of adhesion molecule production and alteration of eNOS and endothelin-1 mRNA expression in endothelium by Euphorbia hirta L. through its beneficial beta-amyrin molecule. Molecules, 2014-07-18;19(7):10534-45. 2014-07-18 [PMID: 25045892] (Mouse)		Mouse
Hamers A, Uleman S, van Tiel C, Kruijswijk D, van Stalborch A, Huveneers S, de Vries C, van 't Veer C Limited role of nuclear receptor Nur77 in Escherichia coli-induced peritonitis. Infect Immun, 2013-10-28;82(1):253-64. 2013-10-28 [PMID: 24166953] (Mouse)		Mouse
Marut W, Kavian N, Servettaz A, Hua-Huy T, Nicco C, Chereau C, Weill B, Dinh-Xuan A, Batteux F Amelioration of systemic fibrosis in mice by angiotensin II receptor blockade. Arthritis Rheum, 2013-05-01;65(5):1367-77. 2013-05-01 [PMID: 23335130] (Mouse)		Mouse
Hegde A, Zhang H, Moochhala SM, Bhatia M Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis. J. Leukoc. Biol., 2007-06-12;82(3):678-85. 2007-06-12 [PMID: 17565047] (Mouse)		Mouse

Array DY575

• E-Selectin/CD62E Antibodies
• E-Selectin/CD62E Antibody Pairs
• E-Selectin/CD62E ELISA Kits
• E-Selectin/CD62E Lysate
• E-Selectin/CD62E Proteins and Enzymes
• E-Selectin/CD62E ELISAs