Mindin/Spondin-2 Antibody [Unconjugated]

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Mindin, also known as Spondin-2 and DIL-1 (Differentially expressed in cancerous and non-cancerous lung cells 1) belongs to the F-spondin family of secreted extracellular matrix proteins. Family members are characterized by two N-terminal F-spondin domains (FS1 and FS2), and a third C-terminal thrombospondin type I repeat (TSP-1). Secreted Mindin exists as a disulfide-linked dimer that also forms higher order oligomers. It functions as a pattern recognition receptor for microbes and an adhesion molecule for neurons. Mindin is secreted by neurons, macrophages and fibroblasts in a variety of tissues. Human Mindin shares 88% amino acid sequence homology with mouse and rat proteins.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 3 applications: ELISA Development, IHC, Western Blot.

Showing Publications 1 - 4 of 4.

Publications using AF2609	Applications	Species
CD Wiley, S Liu, C Limbad, AM Zawadzka, J Beck, M Demaria, R Artwood, F Alimirah, JA Lopez-Domi, C Kuehnemann, SR Danielson, N Basisty, HG Kasler, TR Oron, PY Desprez, SD Mooney, BW Gibson, B Schilling, J Campisi, P Kapahi SILAC Analysis Reveals Increased Secretion of Hemostasis-Related Factors by Senescent Cells Cell Rep, 2019-09-24;28(13):3329-3337.e5. 2019-09-24 [PMID: 31553904] (Western Blot, Human)	Western Blot	Human
YL Zhang, Q Li, XM Yang, F Fang, J Li, YH Wang, Q Yang, L Zhu, HZ Nie, XL Zhang, MX Feng, SH Jiang, GA Tian, LP Hu, HY Lee, SJ Lee, Q Xia, ZG Zhang SPON2 Promotes M1-like Macrophage Recruitment and Inhibits Hepatocellular Carcinoma Metastasis by Distinct Integrin-Rho GTPase-Hippo Pathways Cancer Res., 2018-02-13;0(0):. 2018-02-13 [PMID: 29440144] (Western Blot, Human)	Western Blot	Human
Jokerst JV, Chen Z, Xu L et al. A Magnetic Bead-Based Sensor for the Quantification of Multiple Prostate Cancer Biomarkers. PLoS One 1/1/2015 [PMID: 26421725]
Qian X, Li C, Pang B Spondin-2 (SPON2), a more prostate-cancer-specific diagnostic biomarker. PLoS ONE, 2012-05-15;7(5):e37225. 2012-05-15 [PMID: 22615945] (ELISA Development, IHC, Western Blot, Human)	ELISA Development, IHC, Western Blot	Human

Array AF2609

• Mindin/Spondin-2 Antibodies
• Mindin/Spondin-2 ELISA Kits
• Mindin/Spondin-2 Lysates
• Mindin/Spondin-2 Proteins
• Mindin/Spondin-2 Proteins and Enzymes