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mGluR3 Antibody - BSA Free

Images

 
Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Anti-GRM3 / MGLUR3 antibody IHC of human Brain, Glioblastoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen ...read more
Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Analysis of anti-GRM3 / MGLUR3 antibody with transfection control.
Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Analysis of anti-GRM3 / MGLUR3 antibody with HEK293 human embryonic kidney cells transfected with GRM3 / MGLUR3.
Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Analysis of anti-GRM3 / MGLUR3 antibody with human brain, coroid plexus at 38 ug/ml.
Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)
Immunohistochemistry-Paraffin: mGluR3 Antibody [NLS3208] - Anti-GRM3 / MGLUR3 antibody IHC of human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Details

Summary
Reactivity Hu, Po, Bv, Eq, Pm, Pm, Mu, Rt, Pm-OrSpecies Glossary
Applications WB, IHC, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

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mGluR3 Antibody - BSA Free Summary

Description
Product can be stored undiluted at 4C for up to 1 month.
Immunogen
Synthetic 16 amino acid peptide from N-terminal extracellular domain of human mGluR3.
Epitope
N-terminal extracellular domain of human
Specificity
Human mGluR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Mouse (94%), Rat (94%), Orangutan (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GRM3
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry 1:10 - 1:500
  • Immunohistochemistry 5-10 ug/ml
  • Immunohistochemistry-Paraffin 5-10 ug/ml
  • Western Blot 1:100 - 1:2000

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Turkey (81%), Chicken (81%), Xenopus (81%).

Packaging, Storage & Formulations

Storage
Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for mGluR3 Antibody - BSA Free

  • GLUR3
  • glutamate receptor, metabotropic 3
  • GPRC1C
  • GPRC1Cglutamate metabotropic receptor 3
  • GRM3
  • mGlu3
  • mGluR3
  • MGLUR3metabotropic glutamate receptor 3

Background

The Metabotropic Glutamate Receptor GRM3 binds L-glutamate, the major excitatory neurotransmitter in the central nervous system, which activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. Metabotropic glutamate receptor Group II includes the GRM2 and GRM3 receptors that are linked to inhibition of the cyclic AMP signaling cascade. GRM3 has been reported in various regions of the brain and spinal cord. ESTs have been isolated from brain, embryo, fetal lung/testis/B-cell, nerve, placenta, prostate, and vessel libraries. Caution: GLUR3 refers to Ionotropic Glutamate Receptor 3, not to Metabotropic Glutamate Receptor 3 (mGLUR3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

View specific protocols for mGluR3 Antibody (NLS3208): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GRM3
Entrez