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Methionine Aminopeptidase 2/METAP2 Antibody [Janelia Fluor® 525]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC, IP, KO
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 525

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-99115AF350
Alexa Fluor 405
NBP2-99115AF405
Alexa Fluor 488
NBP2-99115AF488
Alexa Fluor 532
NBP2-99115AF532
Alexa Fluor 594
NBP2-99115AF594
Alexa Fluor 647
NBP2-99115AF647
Alexa Fluor 700
NBP2-99115AF700
Alexa Fluor 750
NBP2-99115AF750
Allophycocyanin
NBP2-99115APC
Biotin
NBP2-99115B
CoraFluor 1
NBP2-99115CL1
DyLight 350
NBP2-99115UV
DyLight 405
NBP2-99115V
DyLight 488
NBP2-99115G
DyLight 550
NBP2-99115R
DyLight 594
NBP2-99115DL594
DyLight 650
NBP2-99115C
DyLight 680
NBP2-99115FR
DyLight 755
NBP2-99115IR
FITC
NBP2-99115F
HRP
NBP2-99115H
Janelia Fluor 549
NBP2-99115JF549
Janelia Fluor 585
NBP2-99115JF585
Janelia Fluor 635
NBP2-99115JF635
Janelia Fluor 646
NBP2-99115JF646
Janelia Fluor 669
NBP2-99115JF669
PE
NBP2-99115PE
PerCP
NBP2-99115PCP
Unconjugated
NBP2-99115-100ul
mFluor Violet 450 SE
NBP2-99115MFV450
mFluor Violet 500 SE
NBP2-99115MFV500
mFluor Violet 610 SE
NBP2-99115MFV610
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Methionine Aminopeptidase 2/METAP2 Antibody [Janelia Fluor® 525] Summary

Immunogen
Produced in rabbits immunized with purified, recombinant Human Methionine Aminopeptidase 2/METAP2 (Accession#: NP_006829.1; Met1-Tyr478)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
METAP2
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Knockout Validated
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Methionine Aminopeptidase 2/METAP2 Antibody [Janelia Fluor® 525]

  • Amp2
  • eIF-2-associated p67 homolog
  • Initiation factor 2-associated 67 kDa glycoprotein
  • MAP 2
  • MAP2
  • MetAP 2
  • METAP2
  • Methionine Aminopeptidase 2
  • methionyl aminopeptidase 2
  • MNPEP
  • p67
  • p67EC 3.4.11.18
  • p67eIF2
  • Peptidase M 2

Background

METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Methionine
Aminopeptidase 2/META ...
NBP2-99115JF525
Methionine Aminopeptidase 2/METAP2 Antibody [Janelia Fluor® 525]
Species: Hu
Applications: WB, ELISA, IHC, IP, KO

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Bioinformatics

Gene Symbol METAP2