Methionine Aminopeptidase 2/METAP2 Antibody Summary
Description |
This antibody can be stored at 2C to 8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles. |
Immunogen |
Produced in rabbits immunized with purified, recombinant Mouse Methionine Aminopeptidase 2/METAP2 (Uniprot#: O08663; Ala2-Tyr478) |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
METAP2 |
Purity |
Antigen and protein A Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA 1:5000-1:10000
- Immunohistochemistry-Paraffin 1:500-1:2000
- Immunoprecipitation 1-4 uL/mg of lysate
- Western Blot 1:500-1:2000
|
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
0.2 um filtered solution in PBS |
Preservative |
No Preservative |
Purity |
Antigen and protein A Affinity-purified |
Alternate Names for Methionine Aminopeptidase 2/METAP2 Antibody
Background
METAP2 is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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