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Melan-A/MART-1 Antibody (M2-7C10) [DyLight 650]

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Product Details

Summary
Reactivity Hu, Eq, Rt(-)Species Glossary
Applications WB, Flow, IHC
Clone
M2-7C10
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 650

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-33148AF350
Alexa Fluor 405
NBP2-33148AF405
Alexa Fluor 488
NBP2-33148AF488
Alexa Fluor 532
NBP2-33148AF532
Alexa Fluor 594
NBP2-33148AF594
Alexa Fluor 647
NBP2-33148AF647
Alexa Fluor 700
NBP2-33148AF700
Alexa Fluor 750
NBP2-33148AF750
Allophycocyanin
NBP2-33148APC-100ul
Allophycocyanin
NBP2-33148APC
Biotin
NBP2-33148B
DyLight 350
NBP2-33148UV
DyLight 405
NBP2-33148V
DyLight 488
NBP2-33148G
DyLight 550
NBP2-33148R
DyLight 594
NBP2-33148DL594
DyLight 680
NBP2-33148FR
DyLight 755
NBP2-33148IR
FITC
NBP2-33148F
HRP
NBP2-33148H
Janelia Fluor 549
NBP2-33148JF549
Janelia Fluor 646
NBP2-33148JF646
PE
NBP2-33148PE
PE
NBP2-33148PE-100ul
PerCP
NBP2-33148PCP
Unconjugated
NBP2-15197-0.1mg
mFluor Violet 450 SE
NBP2-33148MFV450
mFluor Violet 500 SE
NBP2-33148MFV500
mFluor Violet 610 SE
NBP2-33148MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-15197-0.1mg
Azide and BSA Free
NBP2-33148
IHC-Prediluted
NBP2-44386
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Melan-A/MART-1 Antibody (M2-7C10) [DyLight 650] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Recombinant Melan-A/MART-1 protein (Uniprot: Q16655)
Localization
Cytoplasmic
Marker
Melanoma Marker
Specificity
This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This monoclonal antibody labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin.
Isotype
IgG2b Lambda
Clonality
Monoclonal
Host
Mouse
Gene
MLANA
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot

Reactivity Notes

Does not react with Rat.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Melan-A/MART-1 Antibody (M2-7C10) [DyLight 650]

  • Antigen LB39-AA
  • Antigen SK29-AA
  • Mart 1 Melan A
  • MART-1
  • MART1MART-1
  • MelanA
  • Melan-A
  • melanoma antigen recognized by T-cells 1
  • MLANA
  • Protein Melan-A

Background

MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol MLANA
Entrez