Reactivity | Hu, Mu, Rt, CaSpecies Glossary |
Applications | WB, Flow, ICC/IF, IHC, CyTOF-ready |
Clone | A103 + M2-7C10 + M2-9E3 |
Clonality | Monoclonal |
Host | Mouse |
Conjugate | HRP |
Description | This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet. |
Immunogen | Recombinant full-length hMelan-A/MART-1 protein (A103; M2-7C10; M2-9E3) (Uniprot: Q16655) |
Localization | Cytoplasmic |
Marker | Melanoma Marker |
Specificity | This antibody recognizes a protein doublet of 20-22kDa, identified as MART-1 (Melanoma Antigen Recognized by T cells 1) or Melan-A. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Seven other melanoma associated antigens recognized by autologous cytotoxic T cells include MAGE-1, MAGE-3, tyrosinase, gp100, gp75, BAGE-1, and GAGE-1. Subcellular fractionation shows that MART-1 is present in melanosomes and endoplasmic reticulum. This monoclonal antibody cocktail labels melanomas and other tumors showing melanocytic differentiation. It is also a useful positive-marker for angiomyolipomas. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. |
Isotype | IgG1 Kappa/IgG2b Lambda/IgG2b Kappa |
Clonality | Monoclonal |
Host | Mouse |
Gene | MLANA |
Purity | Protein A or G purified |
Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
Dilutions |
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Readout System |
Storage | Store at 4C in the dark. |
Buffer | PBS |
Preservative | No Preservative |
Purity | Protein A or G purified |
Secondary Antibodies |
Isotype Controls |
Research Areas for Melan-A/MART-1 Antibody (NBP2-34546H)Find related products by research area.
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Gene Symbol | MLANA |