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MCT2 Antibody

Images

 
Western Blot: MCT2 Antibody [NBP1-87846] - Analysis in control (vector only transfected HEK293T lysate) and SLC16A7 over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T ...read more
Immunohistochemistry-Paraffin: MCT2 Antibody [NBP1-87846] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neuronal cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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MCT2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: GPNQTTSKSKNKTGKTEDDSSPKKIKTKKSTWEKVNKYLDFS
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLC16A7
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
MCT2 Protein (NBP1-87846PEP)
Publications
Read Publication using NBP1-87846.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for MCT2 Antibody

  • MCT 2
  • MCT2
  • MCT2solute carrier family 16 (monocarboxylic acid transporters), member 7
  • monocarboxylate transporter 2
  • SLC16A7
  • Solute carrier family 16 member 7
  • solute carrier family 16, member 7 (monocarboxylic acid transporter 2)

Background

Lactic acid and pyruvate transport across plasma membranes is catalyzed by members of the proton-linked monocarboxylate transporter (MCT) family, which has been designated solute carrier family 16. Each MCT appears to have slightly different substrate and inhibitor specificities and transport kinetics, which are related to the metabolic requirements of the tissues in which it is found. MCT2 is a high affinity transporter that catalyzes the rapid transport of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate across the plasma membrane.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for MCT2 Antibody (NBP1-87846)(1)

We have publications tested in 1 application: WB.


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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SLC16A7