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SLC5A8/SMCT1 Antibody (903502)

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MCF‑7 human breast cancer cell line was stained with Mouse Anti-Human SLC5A8/SMCT1 Monoclonal Antibody (Catalog # MAB8398, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by Allophycocyanin-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # F0101B).
MCF‑7 human breast cancer cell line was stained with Mouse Anti-Human SLC5A8/SMCT1 Monoclonal Antibody (Catalog # MAB8398, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by ...read more
HEK293 human embryonic kidney cell line transfected with human SLC5A8/SMCT1 and eGFP was stained with either (A) Mouse Anti-Human SLC5A8/SMCT1 Monoclonal Antibody (Catalog # MAB8398) or (B) Mouse IgG1 Isotype Control ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
903502
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
FAB8398U-100UG
Alexa Fluor 405
FAB8398V-100UG
Alexa Fluor 488
FAB8398G-100UG
Alexa Fluor 532
FAB8398X
Alexa Fluor 594
FAB8398T-100UG
Alexa Fluor 647
FAB8398R-100UG
Alexa Fluor 700
FAB8398N-100UG
Alexa Fluor 750
FAB8398S-100UG
Allophycocyanin/Cy7
FAB8398APCCY7
Biotin
FAB8398B
CoraFluor 1
FAB8398CL1
DyLight 350
FAB8398D
DyLight 405
FAB8398E
DyLight 488
FAB8398K
DyLight 550
FAB8398L
DyLight 594
FAB8398M
DyLight 650
FAB8398W
DyLight 680
FAB8398Y
DyLight 755
FAB8398Z
FITC
FAB8398F
HRP
FAB8398H
Janelia Fluor 525
FAB8398JF525
Janelia Fluor 549
FAB8398I
Janelia Fluor 646
FAB8398J
Janelia Fluor 669
FAB8398JF669
PE
FAB8398P
PE/Atto594
FAB8398PEATT594
PE/Cy5.5
FAB8398PECY55
PE/Cy7
FAB8398PECY7
PerCP
FAB8398C
mFluor Violet 450 SE
FAB8398MFV450
mFluor Violet 500 SE
FAB8398MFV500
mFluor Violet 610 SE
FAB8398MFV610
View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB8398-SP
Carrier Free
FAB8398V-100UG
Carrier Free
FAB8398U-100UG
Carrier Free
FAB8398T-100UG
Carrier Free
FAB8398S-100UG
Carrier Free
FAB8398R-100UG
Carrier Free
FAB8398N-100UG
Carrier Free
FAB8398G-100UG
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SLC5A8/SMCT1 Antibody (903502) Summary

Immunogen
NS0 mouse myeloma cell line transfected with human SLC5A8/SMCT1
Met1-Leu610
Accession # NP_666018
Specificity
Detects HEK293 human embryonic kidney cell line transfected with human SLC5A8/SMCT1 by Flow Cytometry. Does not detect untransfected or irrelevant transfected HEK293 cells.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SLC5A8
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SLC5A8/SMCT1 Antibody (903502)

  • AIT
  • AITSolute carrier family 5 member 8
  • Apical iodide transporter
  • Electrogenic sodium monocarboxylate cotransporter
  • MGC125354
  • SLC5A8
  • SMCT
  • SMCTSMCT1
  • Sodium iodide-related cotransporter
  • sodium-coupled monocarboxylate transporter 1
  • solute carrier family 5 (iodide transporter), member 8

Background

SLC5A8/SMCT1 (Solute Carrier family 5, member 8) is a member of the solute carrier family of multi-pass membrane proteins. SLC5A8 has been shown to transport iodide by a passive mechanism. It also transports monocarboxylates and short-chain fatty acids by a sodium-coupled mechanism. SLC5A8 nuclear translocation and loss of expression are associated with poor outcome in pancreatic ductal adenocarcinoma (1). It may be responsible for the absorption of D-lactate and monocarboxylate drugs from the intestinal tract.
  1. Helm, J. et al. (2012) Pancreas 41:904.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SLC5A8
Uniprot