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Marapsin/Pancreasin Antibody (243305)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clone
243305
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

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Marapsin/Pancreasin Antibody (243305) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human Marapsin/Pancreasin
Ala23-Lys290
Accession # Q9BQR3
Specificity
Detects human Marapsin/Pancreasin in direct ELISAs and Western blots. Reacts with an epitope within the mature chain. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse Marapsin is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
PRSS27
Purity Statement
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 25 ug/mL
  • Western Blot 1 ug/mL

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Marapsin/Pancreasin Antibody (243305)

  • CAP-2
  • CAPH2
  • channel-activating protease 2
  • EC 3.4.21
  • EC 3.4.21.-
  • EC 3.4.21.4
  • EC 3.4.21.43
  • Marapsin
  • MPN
  • MPNMarapsin
  • Pancreasin
  • protease, serine 27
  • PRSS27
  • serine protease 27

Background

Marapsin, pancreasin, and channel-activating protease 2 (CAP-2) are different names for the same serine protease that is expressed strongly in the pancreas (1, 2). The protein is synthesized with a signal peptide (amino acids 1‑22), a pro peptide (aa 23‑34) and a mature chain (aa 35‑290) corresponding to the serine protease domain.

  1. Bhagwandin, V.J. et al. (2003) J. Biol. Chem. 278:3363.
  2. Edwards, K.M. et al. (1999) J. Biol. Chem. 274:30468.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PRSS27
Uniprot