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Lymphotoxin beta R/TNFRSF3 Antibody (MM0461-3T24) [Biotin]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
MM0461-3T24
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-11947AF350
Alexa Fluor 405
NBP2-11947AF405
Alexa Fluor 488
NBP2-11947AF488
Alexa Fluor 532
NBP2-11947AF532
Alexa Fluor 594
NBP2-11947AF594
Alexa Fluor 647
NBP2-11947AF647
Alexa Fluor 700
NBP2-11947AF700
Alexa Fluor 750
NBP2-11947AF750
Allophycocyanin
NBP2-11947APC
Allophycocyanin/Cy7
NBP2-11947APCCY7
CoraFluor 1
NBP2-11947CL1
DyLight 350
NBP2-11947UV
DyLight 405
NBP2-11947V
DyLight 488
NBP2-11947G
DyLight 550
NBP2-11947R
DyLight 594
NBP2-11947DL594
DyLight 650
NBP2-11947C
DyLight 680
NBP2-11947FR
DyLight 755
NBP2-11947IR
FITC
NBP2-11947F
HRP
NBP2-11947H
Janelia Fluor 525
NBP2-11947JF525
Janelia Fluor 549
NBP2-11947JF549
Janelia Fluor 646
NBP2-11947JF646
Janelia Fluor 669
NBP2-11947JF669
PE
NBP2-11947PE
PE/Atto594
NBP2-11947PEATT594
PE/Cy5.5
NBP2-11947PECY55
PE/Cy7
NBP2-11947PECY7
PerCP
NBP2-11947PCP
Unconjugated
NBP2-11947
mFluor Violet 450 SE
NBP2-11947MFV450
mFluor Violet 500 SE
NBP2-11947MFV500
mFluor Violet 610 SE
NBP2-11947MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-11947
Azide and BSA Free
NBP2-11947
Azide and BSA Free
NBP2-11947-0.025mg
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Lymphotoxin beta R/TNFRSF3 Antibody (MM0461-3T24) [Biotin] Summary

Description
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Immunogen
Human recombinant Lymphotoxin beta R/TNFRSF3 (extracellular domain)
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
LTBR
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for Lymphotoxin beta R/TNFRSF3 Antibody (MM0461-3T24) [Biotin]

  • CD18
  • D12S370
  • ltbetar
  • LT-BETA-R
  • LTBR
  • lymphotoxin B receptor
  • Lymphotoxin beta R
  • lymphotoxin beta receptor (TNFR superfamily, member 3)
  • Lymphotoxin-beta receptor
  • LymphotoxinbR
  • TNF RIII
  • TNF Rrp
  • TNFCRTNF-RIII
  • TNFR superfamily, member 3
  • TNFR2-RP
  • TNFR3
  • TNF-R-III
  • TNFR-RP
  • TNFRSF3
  • TNFRSF3TNFR-III
  • Tumor necrosis factor C receptor
  • Tumor necrosis factor receptor 2-related protein
  • tumor necrosis factor receptor superfamily member 3
  • tumor necrosis factor receptor superfamily, member 3
  • Tumor necrosis factor receptor type III

Background

LT-beta-R, also known as lymphotoxin beta receptor and tumor necrosis factor receptor superfamily member 3 is a 47 kD transmembrane protein containing 3 TNF receptor domains. The LT-beta-R is a receptor for the heterotrimeric lymphotoxin complex (composed of LT alpha and LT beta as well as LIGHT. LT-beta-R is highly expressed in the lung, liver, and kidney and moderately expressed expressed in the heart and testes. LT-beta-R is weakly expressed in the brain, thymus, spleen, and lymph nodes. The cytoplasmic tail of LT-beta-R interacts with TRAF3, TRAF4, and TRAF5 as well as the hepatitis C virus core protein. Ligand binding to LT-beta-R has been shown to induce apoptosis (via TRAF3 and TRAF5) and play a role in the development of lymphoid organs.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol LTBR