| Reactivity | HuSpecies Glossary |
| Applications | PAGE |
| Concentration | 1 mg/ml |
| Description | A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 169-417 of Human LOX Source: E.coli Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSDDPYNPY KYSDDNPYYN YYDTYERPRP GGRYRPGYGT GYFQYGLPDL VADPYYIQAS TYVQKMSMYN LRCAAEENCL ASTAYRADVR DYDHRVLLRF PQRVKNQGTS DFLPSRPRYS WEWHSCHQHY HSMDEFSHYD LLDANTQRRV AEGHKASFCL EDTSCDYGYH RRFACTAHTQ GLSPGCYDTY GADIDCQWID ITDVKPGNYI LKVSVNPSYL VPESDYTNNV VRCDIRYTGH HAYASGCTIS PY |
| Source | E. coli |
| Protein/Peptide Type | Recombinant Protein |
| Gene | LOX |
| Purity | >85%, by SDS-PAGE |
| Dilutions |
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| Application Notes | Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays. |
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| Theoretical MW | 31.4 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
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| Publications |
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| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer | 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol |
| Preservative | No Preservative |
| Concentration | 1 mg/ml |
| Purity | >85%, by SDS-PAGE |
| Publications using NBP2-59887 | Applications | Species |
|---|---|---|
| Syrkis J, Kujawa K, Zembala-Nozynska E Et al. 711 Evaluation of the LOX gene/protein as potential prognostic marker in ovarian cancer Ovarian cancer 2021-10-01 | ||
| Seborova K, Hlavac V, Rob L Et al. 707 Non-coding RNA and mRNA transcriptome differences in ovarian carcinoma patients associated with resistance to adjuvant chemotherapy Ovarian cancer 2021-10-01 (WB, IF/IHC) | WB, IF/IHC |
Research Areas for LOX Recombinant Protein (NBP2-59887)Find related products by research area.
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LOX: A prime enzyme LOX is a copper-dependent amine oxidase enzyme that executes post-translational oxidative deamination on peptidyl lysine residues in precursors of fibrous collagen and elastin. LOX is secreted into the extracellular environment in an inactive form, wh... Read full blog post. |
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Understanding DNA Recombination with Cre-Lox Cyclization recombination enzyme (Cre) is a member of the extensive family of recombinases and recognizes a 34 bp sequence motif from PI bacteriophage referred to as LoxP. The Cre enzyme works to cleanly excise an intervening DNA fragment that is flan... Read full blog post. |
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Cre/Lox: The Genomic Utility Knife Cre (Cyclization recombination enzyme) is a member of the large family of recombinases. Cre recognizes Lox site loxP, a 34 bp sequence motif from the PI bateriophage. If a DNA segment is flanked by two loxP sites in the same orientation, Cre neatly ex... Read full blog post. |
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LOX propeptide: A novel peptide cancer therapeutic Lysyl oxidase, also known as LOX, is a copper-dependent enzyme that cross-links collagen and elastin through the oxidative deamination of peptidyl lysine (collagen and elastin) and hydroxylysine (collagen only) residues, thereby playing a critical rol... Read full blog post. |
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| Gene Symbol | LOX |
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