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KDEL Antibody (1F2) [DyLight 488]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB
Clone
1F2
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 405
NBP2-61924AF405
Alexa Fluor 488
NBP2-61924AF488
Alexa Fluor 647
NBP2-61924AF647
Alexa Fluor 700
NBP2-61924AF700
Biotin
NBP2-61924B
DyLight 350
NBP2-61924UV
DyLight 405
NBP2-61924V
DyLight 550
NBP2-61924R
DyLight 650
NBP2-61924C
DyLight 680
NBP2-61924FR
DyLight 755
NBP2-61924IR
HRP
NBP2-61924H
Unconjugated
NBP2-61924
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KDEL Antibody (1F2) [DyLight 488] Summary

Immunogen
KDEL peptide (C-AVKDEL -COOH) conjugated at the N-terminal to Bovine Serum Albumin (BSA)
Specificity
Detects KDEL tagged proteins.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
POGLUT2
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for KDEL Antibody (1F2) [DyLight 488]

  • Endoplasmic reticulum resident protein 58
  • EP58KDEL1
  • ER protein 58
  • ERp58
  • KDEL (Lys-Asp-Glu-Leu) containing 1
  • KDEL motif-containing 1
  • KDEL motif-containing protein 1
  • MGC5302

Background

The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble endoplasmic reticulum (ER) resident proteins and some membrane proteins. 78 and 94 kDa glucose regulated proteins (GRP 78) and GRP 94 respectively and protein disulfide isomerase (PDI) all share the C-terminal KDEL sequence. The presence of carboxy-terminal KDEL appears to be necessary for ER retention and appears to be sufficient to reduce the secretion of proteins from the ER. This retention is reported to be mediated by a KDEL receptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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NBP2-61924G
KDEL Antibody (1F2) [DyLight 488]
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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol POGLUT2