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KCC3/SLC12A6 Antibody

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Western Blot:[NBP3-30600]-Detection of human KCC3 by western blot. Samples: Whole cell lysate prepared using RIPA buffer from HeLa, HEK293T, and Jurkat cells. Antibodies: Affinity purified rabbit anti-KCC3 antibody used for WB at 0. 1 µg/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Western Blot:[NBP3-30600]-Detection of human KCC3 by western blot. Samples: Whole cell lysate prepared using RIPA buffer from HeLa, HEK293T, and Jurkat cells. Antibodies: Affinity purified rabbit anti-KCC3 antibody used ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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KCC3/SLC12A6 Antibody Summary

Immunogen
Between 25 and 75
Assay Type
[Assay Type]
Sample Volume
[Sample Volume]
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SLC12A6
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-citrate/phosphate buffer, pH 7 to 8
Preservative
0.09% Sodium Azide
Purity
Affinity purified

Alternate Names for KCC3/SLC12A6 Antibody

  • ACCPN
  • agenesis of corpus callosum and peripheral neuropathy (Andermann syndrome)
  • DKFZp434D2135
  • EC 1.2.4.1
  • EC 6.1.1.3
  • Electroneutral potassium-chloride cotransporter 3
  • KCC3
  • KCC3A
  • KCC3B
  • KCC3potassium chloride cotransporter 3
  • K-Cl cotransporter 3
  • potassium chloride cotransporter KCC3a-S3
  • potassium-chloride transporter-3a
  • potassium-chloride transporter-3b
  • SLC12A6
  • solute carrier family 12 (potassium/chloride transporters), member 6
  • solute carrier family 12 member 6

Background

SLC12A6 is a member of the K-Cl cotransporter (KCC) family. K-Cl cotransporters are integral membrane proteins that lower intracellular chloride concentrations below the electrochemical equilibrium potential. The proteins encoded by this gene are activated by cell swelling induced by hypotonic conditions. Alternate splicing results in multiple transcript variants encoding different isoforms. Mutations in this gene are associated with agenesis of the corpus callosum with peripheral neuropathy. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SLC12A6