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Images
Human peripheral blood monocytes were stained with Human LILRA2/CD85h/ILT1 Monoclonal Antibody (Catalog # MAB6364, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by ...read more
Human peripheral blood monocytes were stained with Human LILRA2/CD85h/ILT1 Monoclonal Antibody (Catalog # MAB6364, filled histogram) or isotype control antibody (Catalog # MAB002, open histogram), followed by ...read more
Mouse myeloma cell line NS0-derived recombinant human LILRA2/CD85h/ILT1 Pro17-Ser437 Accession # Q8N149
Specificity
Detects human LILRA2/CD85h/ILT1 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) ILT2, 3, 4, 5, rhLIR6, or rhLIR8 is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
LILRA2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for ILT1/CD85h/LILRA2 Antibody (600007)
CD85 antigen-like family member H
CD85h antigen
CD85h
ILT1
ILT-1
ILT1CD85H
Leukocyte immunoglobulin-like receptor 7
leukocyte immunoglobulin-like receptor subfamily A member 2 soluble
leukocyte immunoglobulin-like receptor subfamily A member 2
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 2
LILRA2
LIR7
LIR7LIR-7Immunoglobulin-like transcript 1
Background
Immune-like transcript 1 (ILT1), also known as leukocyte immunoglobulin-like receptor 7 (LIR-7), leukocyte immunoglobulin-like receptor subfamily A member 2 (LILRA2), and CD85H, is a 51 kDa (unglycosylated) type I transmembrane glycoprotein and member of the leukocyte immunoglobulin-like receptor family. Human ILT1 is synthesized as a 483 amino acid (aa) precursor that contains a 23 aa signal sequence, a 426 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 13 aa cytoplasmic region. The ECD contains four Ig-like C2-type domains and seven potential sites for N-linked glycosylation. A splice variant produces a second isoform that has a one aa substitution for aa 419-436 in the longer form. There are no murine orthologs for human ILT1. ILT1 may act as a receptor for class I MHC antigens.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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