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ILT1/CD85h/LILRA2 Antibody (600007) [Allophycocyanin]

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Product Details

Summary
Applications Flow
Clone
600007
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

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ILT1/CD85h/LILRA2 Antibody (600007) [Allophycocyanin] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human ILT1/CD85h
Pro17-Ser437
Accession # Q8N149
Specificity
Detects human ILT1/CD85h in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) ILT2, 3, 4, 5, rhLIR6, or rhLIR8 is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
LILRA2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Immune-Like Transcript 1 (ILT1), also known as Leukocyte Immunoglobulin-like Receptor 7 (LIR-7), Leukocyte Immunoglobulin-like Receptor subfamily A member 2 (LILRA2), and CD85h, is a 51 kDa (unglycosylated) type I transmembrane glycoprotein and member of the leukocyte immunoglobulin-like receptor family. Human ILT1 is synthesized as a 483 amino acid (aa) precursor that contains a 23 aa signal sequence, a 426 aa extracellular domain (ECD), a 21 aa transmembrane segment, and a 13 aa cytoplasmic region. The ECD contains four Ig-like C2-type domains and seven potential sites for N-linked glycosylation. A splice variant produces a second isoform that has a one aa substitution for aa 419-436 in the longer form. There are no murine orthologs for human ILT1. ILT1 may act as a receptor for class I MHC antigens.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol LILRA2