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LILRA1/LILRB1 Antibody (586326) [Unconjugated]

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Human blood-derived monocytes were stained with Mouse Anti-Human LILRA1/LILRB1 Monoclonal Antibody (Catalog # MAB30851, filled histogram) or isotype control antibody (Catalog # MAB0041, open histogram), followed by ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
586326
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

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LILRA1/LILRB1 Antibody (586326) [Unconjugated] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human LILRA1
Pro17-Asn461
Accession # O75019
Specificity
Detects human LILRA1 in direct ELISAs. In direct ELISAs, 100% cross-reactivity with recombinant human (rh) LILRB1 is observed and no cross-reactivity rhILT3, 4, 5, 6, rhLIR-7 or -8 is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
LILRA1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry 0.25 ug/10^6 cells
Publications
Read Publication using
MAB30851 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for LILRA1/LILRB1 Antibody (586326) [Unconjugated]

  • CD85I
  • LILRA1/LILRB1
  • LIR6
  • LIR-6

Background

Leukocyte Immunoglobulin-like Receptor 6 (LIR-6), also called LILRA1 or CD85i, is a glycoprotein member of the LIR family of leukocyte Ig-like receptors. As an activating LIR, LIR-6 has a short cytoplasmic tail and a charged aa within the TM domain which interacts with FcR gamma . Both four (LIR-6a) and two (LIR-6b) Ig-like domain forms are expressed by monocytes and B cells. Human LIR-6 has no non-primate ortholog, but shows up to 80% aa identity with human ILT-1c and KIR-p91/PIR-B. A mouse homolog, gp49B2, has structural similarity but limited sequence identity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for LILRA1/LILRB1 Antibody (MAB30851)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: Flow Cytometry.


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FAQs for LILRA1/LILRB1 Antibody (MAB30851) (0)

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Secondary Antibodies

 

Isotype Controls

Additional LILRA1/LILRB1 Products

Array MAB30851

Blogs on LILRA1/LILRB1

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Bioinformatics

Gene Symbol LILRA1
Uniprot