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IL-27 Antibody (307426) [DyLight 488]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications CyTOF-ready, Flow
Clone
307426
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 488

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC25261U-100UG
Alexa Fluor 405
IC25261V-100UG
Alexa Fluor 488
IC25261G-100UG
Alexa Fluor 532
FAB25261X
Alexa Fluor 594
IC25261T-100UG
Alexa Fluor 647
IC25261R-100UG
Alexa Fluor 700
IC25261N-100UG
Alexa Fluor 750
IC25261S-100UG
Allophycocyanin
IC25261A
Biotin
FAB25261B
CoraFluor 1
FAB25261CL1
DyLight 350
FAB25261D
DyLight 405
FAB25261E
DyLight 550
FAB25261L
DyLight 594
FAB25261M
DyLight 650
FAB25261W
DyLight 680
FAB25261Y
DyLight 755
FAB25261Z
Fluorescein
IC25261F
HRP
FAB25261H
Janelia Fluor 525
FAB25261JF525
Janelia Fluor 549
FAB25261I
Janelia Fluor 646
FAB25261J
Janelia Fluor 669
FAB25261JF669
PerCP
FAB25261C
Phycoerythrin
IC25261P
Unconjugated
MAB25261
mFluor Violet 450 SE
FAB25261MFV450
mFluor Violet 500 SE
FAB25261MFV500
mFluor Violet 610 SE
FAB25261MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB25261
Carrier Free
MAB25261
Carrier Free
IC25261A
Carrier Free
IC25261F
Carrier Free
IC25261P
Carrier Free
MAB25261-SP
Carrier Free
IC25261V-100UG
Carrier Free
IC25261U-100UG
Carrier Free
IC25261T-100UG
Carrier Free
IC25261S-100UG
Carrier Free
IC25261R-100UG
Carrier Free
IC25261N-100UG
Carrier Free
IC25261G-100UG
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IL-27 Antibody (307426) [DyLight 488] Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human IL‑27
Arg21-Lys229 of EBI-3 (Accession #Q14213.2) and Phe29-Pro243 of p28 (Accession #AAM34498)
Specificity
Detects human IL-27 in direct ELISAs.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
IL27
Purity
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Intracellular Staining by Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for IL-27 Antibody (307426) [DyLight 488]

  • IL-27 p28 subunit
  • IL-27 subunit alpha
  • IL27
  • IL-27
  • IL27A
  • IL-27-A
  • IL27-A
  • IL27p28
  • IL30
  • interleukin 27
  • interleukin 30
  • interleukin-27 subunit alpha
  • MGC71873
  • p28IL-27A

Background

IL27 is encoded by this gene is one of the subunits of a heterodimeric cytokine complex. This protein is related to interleukin 12A (IL12A). It interacts with Epstein-Barr virus induced gene 3 (EBI3), a protein similar to interleukin 12B (IL12B), and forms a complex that has been shown to drive rapid expansion of naive but not memory CD4(+) T cells. The complex is also found to synergize strongly with interleukin 12 to trigger interferon gamma (IFNG) production of naive CD4(+) T cells. The biological effects of this cytokine are mediated by the class I cytokine receptor (WSX1/TCRR).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol IL27