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IFN-gamma R1/CD119 Antibody (1F1.93.2)

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clone
1F1.93.2
Clonality
Monoclonal
Host
Hamster
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB10261-SP
Carrier Free
MAB10261-500
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IFN-gamma R1/CD119 Antibody (1F1.93.2) Summary

Immunogen
E. coli-derived recombinant mouse IFN‑ gamma R1/CD119
Extracellular domain
Specificity
Detects mouse IFN‑ gamma R1/CD119 in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross‑reactivity with recombinant human (rh) IFN-gamma R1, rhIFN-gamma R2, or rhIL-10 R beta is observed.
Source
N/A
Isotype
IgG
Clonality
Monoclonal
Host
Hamster
Gene
IFNGR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
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Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
Publications
Read Publications using
MAB10261 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IFN-gamma R1/CD119 Antibody (1F1.93.2)

  • AVP, type 2
  • CD119 antigen
  • CD119
  • FLJ45734
  • IFN-gamma R1
  • IFN-gamma receptor 1
  • IFNgammaR1
  • IFN-gamma-R1
  • IFNGR
  • IFNGR1
  • IFN-gR1
  • immune interferon receptor 1
  • interferon gamma receptor 1
  • interferon-gamma receptor alpha chain
  • type 2

Background

The high-affinity IFN-gamma receptor complex is made up of two type I membrane proteins, IFN-gamma R1 (IFN-gamma R alpha ) and IFN-gamma R2 (IFN-gamma R beta ). Both proteins are members of the type II cytokine receptor family and share approximately 52% overall sequence identity. IFN-gamma R1 is the ligand-binding subunit that is necessary and sufficient for IFN-gamma binding and receptor internalization. IFN-gamma R2 is required for IFN-gamma signaling but does not bind IFN-gamma by itself. Human IFN-gamma R1 cDNA encodes a 499 amino acid (aa) protein with a 17 aa signal peptide, a 228 aa extracellular domain, a 23 aa transmembrane domain, and a 221 aa intracellular domain. Human and mouse IFN‑ gamma  R1 share 52% amino acid sequence identity and bind IFN-gamma in a species-specific manner. IFN-gamma R1 is constitutively expressed in most cell types. Soluble IFN‑ gamma  R1 that binds IFN-gamma has been detected in biological fluids.

  1. Bach, E.A. et al. (1997) Annu. Rev. Immunol. 15:563.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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IFN-gamma R1/CD119
Antibody (1F1.93.2)
MAB10261
IFN-gamma R1/CD119 Antibody (1F1.93.2)
Species: Mu
Applications: WB

Publications for IFN-gamma R1/CD119 Antibody (MAB10261)(2)

We have publications tested in 2 confirmed species: Mouse, Rat.

We have publications tested in 1 application: Western Blot.


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(2)
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Secondary Antibodies

 

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Bioinformatics

Gene Symbol IFNGR1