Home » IFN-gamma R1/CD119 » IFN-gamma R1/CD119 Antibodies » IFN-gamma R1/CD119 Antibody (170911)
Novus Biologicals products are now on bio-techne.com

IFN-gamma R1/CD119 Antibody (170911)

 (1 Publication)
 See All Related
Submit a Review

Images

 
(
Enlarge)
Recombinant Mouse IFN‑ gamma (Catalog # 485-MI) reduces the Encephalomyocarditis Virus (EMCV)-induced cytopathy in the L‑929 mouse fibroblast cell line in a dose-dependent manner (orange line), as measured by Resazurin. Inhibition of EMCV activity elicited by Recombinant Mouse IFN‑ gamma (1 ng/mL) is neutralized (green line) by increasing concentrations of Mouse IFN‑ gamma R1/CD119 Monoclonal Antibody (Catalog # MAB10262). The ND50 is typically 4-20 ng/mL.
Recombinant Mouse IFN‑ gamma (Catalog # 485-MI) reduces the Encephalomyocarditis Virus (EMCV)-induced cytopathy in the L‑929 mouse fibroblast cell line in a dose-dependent manner (orange line), as measured by ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications B/N, ELISA(Cap)
Clone
170911
Clonality
Monoclonal
Host
Rat
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price
Carrier Free
MAB10262-SP
Novus Biologicals is part of Bio-Techne

Shop this product on bio-techne.com

Novus Biologicals, part of Bio-Techne, offers 100% Guarantee

IFN-gamma R1/CD119 Antibody (170911) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse IFN-gamma  R1/CD119
Gly23-Asp253 (predicted)
Accession # NP_034641
Specificity
Detects mouse IFN-gamma R1/CD119 in ELISAs. In sandwich immunoassays, no cross-reactivity or interference with recombinant mouse (rm) IFN‑ alpha / beta  R1, rmIFN-gamma R2, recombinant human (rh) IFN-gamma R1, rhIL-20 R alpha , rhIL-20 R beta , rmIL-20 R alpha , rhIL-22BP or rmIL-22BP is observed.
Source
N/A
Isotype
IgG2b
Clonality
Monoclonal
Host
Rat
Gene
IFNGR1
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Endotoxin Note
<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • ELISA Capture (Matched Antibody Pair) 2-8 ug/mL
  • ELISA Detection (Matched Antibody Pair) 0.1-0.4 ug/mL
  • ELISA Standard (Matched Pair)
  • Neutralization 4-20 ng/mL
Application Notes
ELISA Capture: Mouse IFN-gamma R1/CD119 Antibody (Catalog # MAB10262)
ELISA Detection: Mouse IFN-gamma R1/CD119 Biotinylated Antibody (Catalog # BAF1026)
Standard: Recombinant Mouse IFN-gamma R1/CD119 Fc Chimera (Catalog # 1026-GR)
Publications
Read Publication using
MAB10262 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IFN-gamma R1/CD119 Antibody (170911)

  • AVP, type 2
  • CD119 antigen
  • CD119
  • FLJ45734
  • IFN-gamma R1
  • IFN-gamma receptor 1
  • IFNgammaR1
  • IFN-gamma-R1
  • IFNGR
  • IFNGR1
  • IFN-gR1
  • immune interferon receptor 1
  • interferon gamma receptor 1
  • interferon-gamma receptor alpha chain
  • type 2

Background

The high-affinity IFN-gamma  receptor complex is made up of two type I membrane proteins, IFN-gamma  R1 (IFN-gamma  R alpha ) and IFN-gamma  R2 (IFN-gamma  R beta ). Both proteins are members of the type II cytokine receptor family and share approximately 52% overall sequence identity. IFN-gamma  R1 is the ligand-binding subunit that is necessary and sufficient for IFN-gamma binding and receptor internalization. IFN-gamma  R2 is required for IFN-gamma signaling but does not bind IFN-gamma by itself. Human IFN-gamma  R1 cDNA encodes a 499 amino acid (aa) protein with a 17 aa signal peptide, a 228 aa extracellular domain, a 23 aa transmembrane domain, and a 221 aa intracellular domain. Human and mouse IFN-gamma  R1 share 52% amino acid sequence similarity and bind IFN-gamma in a species-specific manner. IFN-gamma  R1 is constitutively expressed in most cell types. Soluble IFN-gamma  R1 that binds IFN-gamma has been detected in biological fluids.

  1. Bach, E.A. et al. (1997) Annu. Rev. Immunol. 15:563.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

IFN-gamma
[Unconjugated]
285-IF
Bioactivity IFN-gamma [Unconjugated]
SDS-PAGE IFN-gamma [Unconjugated]
SEC-MALS IFN-gamma [Unconjugated]
(2 Reviews)
(453 Publications)
Species: Hu
Applications: BA
STAT1 [p Tyr701]
Antibody [Unconjugate ...
AF2894
Western Blot STAT1 [p Tyr701] Antibody [Unconjugated]
Simple Western STAT1 [p Tyr701] Antibody [Unconjugated]
Intracellular Staining by Flow Cytometry STAT1 [p Tyr701] Antibody [Unconjugated]
(1 Review)
(11 Publications)
Species: Hu, Mu
Applications: CyTOF-ready, ICFlow, Simple Western, WB
IFN-gamma R2
Antibody [Unconjugate
AF773
Neutralization IFN-gamma R2 Antibody [Unconjugated]
Flow Cytometry IFN-gamma R2 Antibody [Unconjugated]
Western Blot IFN-gamma R2 Antibody [Unconjugated]
(5 Publications)
Species: Hu
Applications: CyTOF-ready, Flow, Neut, WB
TNF-alpha
[Unconjugated]
210-TA
SDS-PAGE TNF-alpha [Unconjugated]
Bioactivity TNF-alpha [Unconjugated]
SEC-MALS TNF-alpha [Unconjugated]
(3 Reviews)
(817 Publications)
Species: Hu
Applications: BA
IL-6 [HRP]
M6000B
N/A IL-6 [HRP]
N/A IL-6 [HRP]
N/A IL-6 [HRP]
(663 Publications)
Species: Mu
Applications: ELISA
IL-12 R beta 1
Antibody [Unconjugate
AF839
IL-12 R beta 1 Antibody [Unconjugated]
(3 Publications)
Species: Hu
Applications: WB
IL-4 [Unconjugated]
6507-IL/CF
Bioactivity IL-4 [Unconjugated]
(3 Publications)
Species: Hu
Applications: BA
IL-12/IL-23 p40
[Biotin]
DY499
N/A IL-12/IL-23 p40 [Biotin]
(51 Publications)
Species: Mu
Applications: ELISA
IL-10 [Biotin]
DY417
N/A IL-10 [Biotin]
(302 Publications)
Species: Mu
Applications: ELISA
IFN-alpha 1
Antibody
NBP2-75930
Western Blot IFN-alpha 1 Antibody
Immunocytochemistry/ Immunofluorescence IFN-alpha 1 Antibody
Immunocytochemistry/ Immunofluorescence IFN-alpha 1 Antibody
Species: Hu, Mu, Rt
Applications: Flow, ICC/IF, IHC, IHC-P, WB
Jak1 Antibody
(413104) [Unconjugate
MAB4260
Western Blot Jak1 Antibody (413104) [Unconjugated]
Immunohistochemistry Jak1 Antibody (413104) [Unconjugated]
Intracellular Staining by Flow Cytometry Jak1 Antibody (413104) [Unconjugated]
(1 Review)
(2 Publications)
Species: Hu, Mu, Rt
Applications: CyTOF-ready, ICC, IHC, ICFlow, Simple Western, WB
IFN-alpha/beta R1
Antibody [Unconjugate ...
AF245
Western Blot IFN-alpha/beta R1 Antibody [Unconjugated]
(9 Publications)
Species: Hu
Applications: CyTOF-ready, Flow, WB
IRF1 Antibody
[Unconjugated]
AF4715
Western Blot IRF1 Antibody [Unconjugated]
Western Blot IRF1 Antibody [Unconjugated]
(1 Review)
(2 Publications)
Species: Mu
Applications: WB
IKK gamma
Inhibitor Peptide Set
NBP2-26504
In vivo assay IKK gamma Inhibitor Peptide Set
In vivo assay IKK gamma Inhibitor Peptide Set
Unknown IKK gamma Inhibitor Peptide Set
(22 Publications)
Species: Hu, Mu, Rt
Applications: B/N, Func-Inh, In vitro, In vivo
IL-1 beta/IL-1F2
[Unconjugated]
201-LB
SDS-PAGE IL-1 beta/IL-1F2 [Unconjugated]
Bioactivity IL-1 beta/IL-1F2 [Unconjugated]
SEC-MALS IL-1 beta/IL-1F2 [Unconjugated]
(594 Publications)
Species: Hu
Applications: BA
CXCL8/IL-8
Antibody (6217) [Unco ...
MAB208
Neutralization CXCL8/IL-8 Antibody (6217) [Unconjugated]
Immunocytochemistry CXCL8/IL-8 Antibody (6217) [Unconjugated]
Western Blot CXCL8/IL-8 Antibody (6217) [Unconjugated]
(1 Review)
(183 Publications)
Species: Hu
Applications: CyTOF-ready, ELISA(Cap), ELISA(Det), ELISA(Sta), ICC, ICFlow, Neut, Simple Western, WB
NOD2 Antibody
(2D9) - BSA Free
NB100-524
Flow Cytometry NOD2 Antibody (2D9) - BSA Free
Flow Cytometry NOD2 Antibody (2D9) - BSA Free
Immunohistochemistry-Frozen NOD2 Antibody (2D9) - BSA Free
(1 Review)
(26 Publications)
Species: Hu, Mu
Applications: Flow-IC, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, IP, WB
IFN-gamma R1/CD119
Antibody (170911)
MAB10262
IFN-gamma R1/CD119 Antibody (170911)
Species: Mu
Applications: B/N, ELISA(Cap)

Publications for IFN-gamma R1/CD119 Antibody (MAB10262)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: Neutralization.


Filter By Application
Neutralization
(1)
All Applications
Filter By Species
Mouse
(1)
All Species

Reviews for IFN-gamma R1/CD119 Antibody (MAB10262) (0)

There are no reviews for IFN-gamma R1/CD119 Antibody (MAB10262). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

FAQs for IFN-gamma R1/CD119 Antibody (MAB10262) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional IFN-gamma R1/CD119 Products

Blogs on IFN-gamma R1/CD119

There are no specific blogs for IFN-gamma R1/CD119, but you can read our latest blog posts.
Read our latest blog and use the new citation tool on bio-techne.com

Contact Information

Product PDFs

  PDF SDS
  PDF Datasheet
  Request CofA

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our IFN-gamma R1/CD119 Antibody (170911) and receive a gift card or discount.


Bioinformatics

Gene Symbol IFNGR1
Uniprot