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ICAM-4 Antibody (729632) [Janelia Fluor® 669]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow, CyTOF-ready
Clone
729632
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 669

Order Details

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ICAM-4 Antibody (729632) [Janelia Fluor® 669] Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human ICAM-4
Ala23-Ala240
Accession # Q14773
Specificity
Detects human ICAM-4 in direct ELISAs.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
ICAM4
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for ICAM-4 Antibody (729632) [Janelia Fluor® 669]

  • CD242 antigen
  • CD242
  • ICAM4
  • ICAM-4
  • intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
  • intercellular adhesion molecule 4 (LW blood group)
  • intercellular adhesion molecule 4
  • intercellular adhesion molecule 4, Landsteiner-Wiener blood group
  • Landsteiner-Wiener blood group antigen a
  • Landsteiner-Wiener blood group glycoprotein
  • Landsteiner-Wiener blood group
  • LWLW blood group protein

Background

ICAM4 encodes the Landsteiner-Wiener (LW) blood group antigen(s) that belongs to the immunoglobulin (Ig) superfamily, and that shares similarity with the intercellular adhesion molecule (ICAM) protein family. This ICAM protein contains 2 Ig-like C2-type domains and binds to the leukocyte adhesion LFA-1 protein. The molecular basis of the LW(A)/LW(B) blood group antigens is a single aa variation at position 100; Gln-100=LW(A) and Arg-100=LW(B). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for ICAM-4 Antibody (FAB8397JF669) (0)

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Secondary Antibodies

 

Isotype Controls

Additional ICAM-4 Products

Blogs on ICAM-4.

Chromatin reader domains of DNMT-targeting protein, UHRF1, are responsible for cancerous DNA hypermethylation
By Jamshed Arslan, Pharm. D., PhD. DNA methylation represses transcription of many genes, including tumor suppressor genes. A protein called UHRF1 recruits DNA methyltransferases (DNMTs) to establish and maintain DNA...  Read full blog post.

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Bioinformatics

Gene Symbol ICAM4