Human ST2/IL-33R Quantikine ELISA Kit

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

ST2, also known as IL-1 R4, is a component of the receptor for the proinflammatory cytokine Interleukin-33. The IL-33 receptor additionally includes IL-1 RAcp which also associates with IL-1 RI and IL-1 R rp2/IL-1 R6. A soluble form of ST2 functions as a decoy receptor. IL-33 promotes Th2-biased immune responses, resulting in eosinophilia, mast cell activation, and allergic inflammation. In addition, IL-33 enhances inflammation-associated hypernociception and protects from atherosclerosis and cardiac myocyte hypertrophy. Soluble ST2 is elevated in the serum under inflammatory conditions including allergic asthma, sepsis, trauma, dengue fever, pulmonary disease, and lupus. It is also associated aortic stenosis, congestive cardiomyopathy, and risk of cardiovascular heart failure and death.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 10 of 38. Show All 38 Publications. Collapse Publications.

Publications using DST200	Applications	Species
Arakelian, L;Lion, J;Churlaud, G;Bargui, R;Thierry, B;Mutabazi, E;Bruneval, P;Alberdi, AJ;Doliger, C;Veyssiere, M;Larghero, J;Mooney, N; Endothelial CD34 expression and regulation of immune cell response in-vitro Scientific reports 2023-08-19 [PMID: 37598252] (Human)		Human
M Gherghe, AM Lazar, MD Mutuleanu, CI Bordea, S Ionescu, RI Mihaila, C Petroiu, AE Stanciu Evaluating Cardiotoxicity in Breast Cancer Patients Treated with HER2 Inhibitors: Could a Combination of Radionuclide Ventriculography and Cardiac Biomarkers Predict the Cardiac Impact? Cancers, 2022-12-29;15(1):. 2022-12-29 [PMID: 36612202] (Human)		Human
E Palà, A Bustamante, JL Clúa-Espun, J Acosta, F González-L, SD Santos, D Ribas-Segu, J Ballesta-O, A Penalba, M Giralt, I Lechuga-Du, D Gentille-L, A Pedrote, MÁ Muñoz, J Montaner Blood-biomarkers and devices for atrial fibrillation screening: Lessons learned from the AFRICAT (Atrial Fibrillation Research In CATalonia) study PLoS ONE, 2022-08-23;17(8):e0273571. 2022-08-23 [PMID: 35998199] (Human)		Human
J Luther, AG Vannier, EA Schaefer, RP Goodman The circulating proteomic signature of alcohol-associated liver disease JCI Insight, 2022-07-22;7(14):. 2022-07-22 [PMID: 35866482] (Human)		Human
P Simeone, R Tripaldi, A Michelsen, T Ueland, R Liani, S Ciotti, KI Birkeland, HL Gulseth, A Di Casteln, F Cipollone, P Aukrust, A Consoli, B Halvorsen, F Santilli Effects of liraglutide vs. lifestyle changes on soluble suppression of tumorigenesis-2 (sST2) and galectin-3 in obese subjects with prediabetes or type 2 diabetes after comparable weight loss Cardiovascular Diabetology, 2022-03-11;21(1):36. 2022-03-11 [PMID: 35277168] (Human)		Human
E Mai, J Chan, L Goon, BK Ego, J Bevers, T Wong, M Wong, R Corpuz, H Xi, J Wu, K Schneider, D Seshasayee, M Grimbaldes, G Nakamura, VB Indjeian, M van Looker, KM Loyet, L Comps-Agra Development of an ultra-sensitive human IL-33 biomarker assay for age-related macular degeneration and asthma drug development Journal of Translational Medicine, 2021-12-20;19(1):517. 2021-12-20 [PMID: 34930320] (Human)		Human
Y Su, Y Sun, Y Tang, H Li, X Wang, X Pan, W Liu, X Zhang, F Zhang, Y Xu, C Yan, SB Ong, D Xu Circulating miR-19b-3p as a Novel Prognostic Biomarker for Acute Heart Failure Journal of the American Heart Association, 2021-10-06;10(20):e022304. 2021-10-06 [PMID: 34612058] (Human)		Human
AM Ambari, B Setianto, A Santoso, B Radi, B Dwiputra, E Susilowati, F Tulrahmi, A Wind, MJM Cramer, P Doevendans Randomised controlled trial into the role of ramipril in fibrosis reduction in rheumatic heart disease: the RamiRHeD trial protocol BMJ Open, 2021-09-13;11(9):e048016. 2021-09-13 [PMID: 34518254] (Human)		Human
Y Yao, L Feng, Y Sun, S Wang, J Sun, B Hu Myocardial fibrosis combined with NT-proBNP improves the accuracy of survival prediction in ADHF patients BMC cardiovascular disorders, 2021-05-28;21(1):264. 2021-05-28 [PMID: 34049488] (Human)		Human
A Cyr, Y Zhong, SE Reis, RA Namas, A Amoscato, B Zuckerbrau, J Sperry, R Zamora, Y Vodovotz, TR Billiar Analysis of the Plasma Metabolome after Trauma, Novel Circulating Sphingolipid Signatures, and In-Hospital Outcomes Journal of the American College of Surgeons, 2021-01-14;0(0):. 2021-01-14 [PMID: 33453380] (Human)		Human
MA Hannappe, L Arnould, A Méloux, B Mouhat, F Bichat, M Zeller, Y Cottin, C Binquet, C Vergely, C Creuzot-Ga, C Guenancia Vascular density with optical coherence tomography angiography and systemic biomarkers in low and high cardiovascular risk patients Sci Rep, 2020-10-07;10(1):16718. 2020-10-07 [PMID: 33028913] (Human)		Human
E Kowalik, A Kwiatek-Wr, A Klisiewicz, A Lutynska, EK Biernacka, M Kowalski, P Hoffman Systemic right ventricle in elderly patients with congenitally corrected transposition of the great arteries: Clinical profile, cardiac biomarkers, and echocardiographic parameters Anatol J Cardiol, 2020-08-01;24(2):92-96. 2020-08-01 [PMID: 32749250] (Human)		Human
M Saresella, I Marventano, F Piancone, F La Rosa, D Galimberti, C Fenoglio, E Scarpini, M Clerici IL-33 and its decoy sST2 in patients with Alzheimer's disease and mild cognitive impairment J Neuroinflammation, 2020-06-06;17(1):174. 2020-06-06 [PMID: 32505187] (Human)		Human
MM Abhyankar, JZ Ma, KW Scully, AJ Nafziger, AL Frisbee, MM Saleh, GR Madden, AR Hays, M Poulter, WA Petri Immune Profiling To Predict Outcome of Clostridioides difficile Infection MBio, 2020-05-26;11(3):. 2020-05-26 [PMID: 32457246] (Human)		Human
FG Scurt, J Menne, S Brandt, A Bernhardt, PR Mertens, H Haller, C Chatzikyrk Systemic Inflammation Precedes Microalbuminuria in Diabetes Kidney Int Rep, 2019-06-21;4(10):1373-1386. 2019-06-21 [PMID: 31701047] (Human)		Human
X Yin, H Cao, Y Wei, HH Li Alteration of the IL-33-sST2 pathway in hypertensive patients and a mouse model Hypertens. Res., 2019-06-24;0(0):. 2019-06-24 [PMID: 31235844] (Human)		Human
AL Frisbee, MM Saleh, MK Young, JL Leslie, ME Simpson, MM Abhyankar, CA Cowardin, JZ Ma, P Pramoonjag, SD Turner, AP Liou, EL Buonomo, WA Petri IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection Nat Commun, 2019-06-20;10(1):2712. 2019-06-20 [PMID: 31221971] (Human)		Human
K Almahmoud, A Abboud, RA Namas, R Zamora, J Sperry, AB Peitzman, MS Truitt, GE Gaski, TO McKinley, TR Billiar, Y Vodovotz Computational evidence for an early, amplified systemic inflammation program in polytrauma patients with severe extremity injuries PLoS ONE, 2019-06-04;14(6):e0217577. 2019-06-04 [PMID: 31163056] (Human)		Human
N Ohta, H Yasudo, M Mizutani, T Matsushige, R Fukano, S Kittaka, K Maehara, K Ichihara, S Ohga, S Hasegawa Serum soluble ST2 as a marker of renal scar in pediatric upper urinary tract infection Cytokine, 2019-05-29;120(0):258-263. 2019-05-29 [PMID: 31153005] (Human)		Human
CK Wu, MM Su, YF Wu, JJ Hwang, LY Lin Combination of Plasma Biomarkers and Clinical Data for the Detection of Myocardial Fibrosis or Aggravation of Heart Failure Symptoms in Heart Failure with Preserved Ejection Fraction Patients J Clin Med, 2018-11-08;7(11):. 2018-11-08 [PMID: 30413105] (Human)		Human
ES Lepojärvi, HV Huikuri, OP Piira, AM Kiviniemi, JA Miettinen, T Kenttä, O Ukkola, JS Perkiömäki, MP Tulppo, MJ Junttila Biomarkers as predictors of sudden cardiac death in coronary artery disease patients with preserved left ventricular function (ARTEMIS study) PLoS ONE, 2018-09-18;13(9):e0203363. 2018-09-18 [PMID: 30226845] (Human)		Human
M Watanabe, K Nakamoto, T Inui, M Sada, K Honda, M Tamura, Y Ogawa, T Yokoyama, T Saraya, D Kurai, H Ishii, H Takizawa Serum sST2 levels predict severe exacerbation of asthma Respir. Res., 2018-09-03;19(1):169. 2018-09-03 [PMID: 30176857] (Human)		Human
ZH Wei, YY Li, SQ Huang, ZQ Tan Genetic variants in IL-33/ST2 pathway with the susceptibility to hepatocellular carcinoma in a Chinese population Cytokine, 2018-04-12;0(0):. 2018-04-12 [PMID: 29656959] (Human)		Human
D Binas, H Daniel, A Richter, V Ruppert, KD Schlüter, B Schieffer, S Pankuweit The prognostic value of sST2 and galectin-3 considering different aetiologies in non-ischaemic heart failure Open Heart, 2018-02-26;5(1):e000750. 2018-02-26 [PMID: 29531765] (Human)		Human
FN Dijk, C Xu, E Melén, AE Carsin, A Kumar, IM Nolte, O Gruzieva, G Pershagen, NS Grotenboer, OEM Savenije, JM Antó, I Lavi, C Dobaño, J Bousquet, P van der Vl, RJP van der Va, JC de Jongste, MC Nawijn, S Guerra, DS Postma, GH Koppelman Genetic regulation ofIL1RL1methylation and IL1RL1-a protein levels in asthma Eur. Respir. J., 2018-03-08;51(3):. 2018-03-08 [PMID: 29519908] (Human)		Human
JE Miller, SP Monsanto, SH Ahn, K Khalaj, AT Fazleabas, SL Young, BA Lessey, M Koti, C Tayade Interleukin-33 modulates inflammation in endometriosis Sci Rep, 2017-12-20;7(1):17903. 2017-12-20 [PMID: 29263351] (Human)		Human
SJ Rotz, CE Dandoy, MD Taylor, S Jodele, JL Jefferies, A Lane, JA El-Bietar, AW Powell, SM Davies, TD Ryan Long-term systolic function in children and young adults after hematopoietic stem cell transplant Bone Marrow Transplant., 2017-07-17;0(0):. 2017-07-17 [PMID: 28714947] (Human)		Human
M Younas, C Psomas, V Mehraj, R Cezar, P Portales, E Tuaillon, A Guigues, J Reynes, P Corbeau, JP Routy Plasma Level of Soluble ST2 in Chronically Infected HIV-1 Patients with Suppressed Viremia Open AIDS J, 2017-04-26;11(0):32-35. 2017-04-26 [PMID: 28553430] (Human)		Human
SJ Rotz, TD Ryan, S Jodele, JL Jefferies, A Lane, A Pate, R Hirsch, J Hlavaty, AE Levesque, MD Taylor, M Cash, KC Myers, JA El-Bietar, SM Davies, CE Dandoy The injured heart: early cardiac effects of hematopoietic stem cell transplantation in children and young adults Bone Marrow Transplant., 2017-04-10;0(0):. 2017-04-10 [PMID: 28394368] (Human)		Human
C Wojciechow, E Romuk, E Nowalany-K, W Jache? Serum Galectin-3 and ST2 as predictors of unfavorable outcome in stable dilated cardiomyopathy patients Hellenic J Cardiol, 2017-03-28;0(0):. 2017-03-28 [PMID: 28363768] (Human)		Human
Targeting LOXL2 for cardiac interstitial fibrosis and heart failure treatment Nat Commun, 2016-12-14;7(0):13710. 2016-12-14 [PMID: 27966531] (Human)		Human
Carotid plaque and bone density and microarchitecture in psoriatic arthritis: the correlation with soluble ST2 Sci Rep, 2016-08-24;6(0):32116. 2016-08-24 [PMID: 27554830] (Human)		Human
AK Fu, KW Hung, MY Yuen, X Zhou, DS Mak, IC Chan, TH Cheung, B Zhang, WY Fu, FY Liew, NY Ip IL-33 ameliorates Alzheimer's disease-like pathology and cognitive decline Proc Natl Acad Sci USA, 2016-04-18;0(0):. 2016-04-18 [PMID: 27091974] (Human)		Human
Sun M, Ma H, Che Y, Cui X Reduced IL-33 plasma levels in aplastic anemia. Cancer Cell Int, 2015-12-16;15(0):118. 2015-12-16 [PMID: 26677348] (Human)		Human
Traister R, Uvalle C, Hawkins G, Meyers D, Bleecker E, Wenzel S Phenotypic and genotypic association of epithelial IL1RL1 to human TH2-like asthma. J Allergy Clin Immunol, 2014-08-01;135(1):92-9. 2014-08-01 [PMID: 25091434] (Human)		Human
Faber TE, Schuurhof A, Vonk A, Koppelman GH, Hennus MP, Kimpen JL, Janssen R, Bont LJ IL1RL1 gene variants and nasopharyngeal IL1RL-a levels are associated with severe RSV bronchiolitis: a multicenter cohort study. PLoS ONE, 2012-05-04;7(5):e34364. 2012-05-04 [PMID: 22574108] (Human)		Human
Miyagaki T, Sugaya M High Levels of Soluble ST2 and Low Levels of IL-33 in Sera of Patients with HIV Infection. J. Invest. Dermatol., 2010-12-09;131(0):794. 2010-12-09 [PMID: 21150924] (Human)		Human
Yagami A, Orihara K, Morita H IL-33 mediates inflammatory responses in human lung tissue cells. J. Immunol., 2010-10-06;185(10):5743-50. 2010-10-06 [PMID: 20926795] (Human)		Human
Show All 38 Publications. Collapse Publications.

Array DST200

• ST2/IL-33R Antibodies
• ST2/IL-33R Antibody Pair
• ST2/IL-33R ELISA Kit
• ST2/IL-33R Proteins
• ST2/IL-33R ELISAs
• ST2/IL-33R Proteins and Enzymes