Human Phospho-VEGFR2/KDR DuoSet IC ELISA, 2 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

VEGF R1 (Flt-1), VEGF R2 (KDR/Flk-1), and VEGF R3 (Flt-4) belong to the class III subfamily of receptor tyrosine kinases (RTKs). All three receptors contain seven immunoglobulin-like repeats in their extracellular domain and kinase insert domains in their intracellular region. They are best known for regulating VEGF family-mediated vasculogenesis, angiogenesis, and lymphangiogenesis. They are also mediators of neurotrophic activity and regulators of hematopoietic development. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 10 of 12. Show All 12 Publications. Collapse Publications.

Publications using DYC1766-2	Applications	Species
T Yao, H Chen, R Wang, R Rivero, F Wang, L Kessels, SM Agten, TM Hackeng, TGAM Wolfs, D Fan, MB Baker, L Moroni Thiol-ene conjugation of VEGF peptide to electrospun scaffolds as potential application for angiogenesis Bioactive materials, 2022-06-08;20(0):306-317. 2022-06-08 [PMID: 35755423] (Human)		Human
L Koehler, G Ruiz-Gómez, K Balamuruga, S Rother, J Freyse, S Möller, M Schnabelra, S Köhling, S Djordjevic, D Scharnwebe, J Rademann, MT Pisabarro, V Hintze Dual Action of Sulfated Hyaluronan on Angiogenic Processes in Relation to Vascular Endothelial Growth Factor-A Sci Rep, 2019-12-02;9(1):18143. 2019-12-02 [PMID: 31792253] (Human)		Human
P Mésange, A Bouygues, N Ferrand, M Sabbah, AE Escargueil, A Savina, B Chibaudel, C Tournigand, T Andre, A de Gramont, AK Larsen Combinations of Bevacizumab and Erlotinib show activity in colorectal cancer independent of RAS status Clin. Cancer Res., 2018-02-28;0(0):. 2018-02-28 [PMID: 29490990] (Human)		Human
M Su, B Qin, F Liu, Y Chen, R Zhang Andrographolide enhanced 5-fluorouracil-induced antitumor effect in colorectal cancer via inhibition of c-MET pathway Drug Des Devel Ther, 2017-11-23;11(0):3333-3341. 2017-11-23 [PMID: 29200829] (Human)		Human
Raquel Costa Modulation of VEGF signaling in a mouse model of diabetes by xanthohumol and 8-prenylnaringenin: Unveiling the angiogenic paradox and metabolism interplay Mol Nutr Food Res, 2017-01-30;0(0):. 2017-01-30 [PMID: 27921359] (Human)		Human
Harris , Nicole C, Davydova , Natalia, Roufail , Sally, Paquet-Fifield , Sophie, Paavonen , Karri, Karnezis , Tara, Zhang , You-Fang, Sato , Teruhiko, Rothacker , Julie, Nice , Edouard, Stacker , Steven A, Achen , Marc G The propeptides of VEGF-D determine heparin binding, receptor heterodimerization, and effects on tumor biology. J Biol Chem, 2013-02-12;288(12):8176-86. 2013-02-12 [PMID: 23404505] (Human)		Human
Gavine PR, Mooney L, Kilgour E AZD4547: an orally bioavailable, potent, and selective inhibitor of the fibroblast growth factor receptor tyrosine kinase family. Cancer Res., 2012-02-27;72(8):2045-56. 2012-02-27 [PMID: 22369928] (Human)		Human
Yamashita-Kashima Y, Fujimoto-Ouchi K, Yorozu K, Kurasawa M, Yanagisawa M, Yasuno H, Mori K Biomarkers for antitumor activity of bevacizumab in gastric cancer models. BMC Cancer, 2012-01-25;12(0):37. 2012-01-25 [PMID: 22273502] (Human)		Human
Martino MM, Hubbell JA The 12th-14th type III repeats of fibronectin function as a highly promiscuous growth factor-binding domain. FASEB J., 2010-07-29;24(12):4711-21. 2010-07-29 [PMID: 20671107] (Human)		Human
Xu Y, Yuan L, Mak J, Pardanaud L, Caunt M, Kasman I, Larrivee B, Del Toro R, Suchting S, Medvinsky A, Silva J, Yang J, Thomas JL, Koch AW, Alitalo K, Eichmann A, Bagri A Neuropilin-2 mediates VEGF-C-induced lymphatic sprouting together with VEGFR3. J. Cell Biol., 2010-01-11;188(1):115-30. 2010-01-11 [PMID: 20065093] (Human)		Human
Pan Q, Chathery Y, Wu Y, Rathore N, Tong RK, Peale F, Bagri A, Tessier-Lavigne M, Koch AW, Watts RJ Neuropilin-1 binds to VEGF121 and regulates endothelial cell migration and sprouting. J. Biol. Chem., 2007-06-16;282(33):24049-56. 2007-06-16 [PMID: 17575273] (Human)		Human
Favier B, Alam A, Barron P, Bonnin J, Laboudie P, Fons P, Mandron M, Herault JP, Neufeld G, Savi P, Herbert JM, Bono F Neuropilin-2 interacts with VEGFR-2 and VEGFR-3 and promotes human endothelial cell survival and migration. Blood, 2006-04-18;108(4):1243-50. 2006-04-18 [PMID: 16621967] (Human)		Human
Show All 12 Publications. Collapse Publications.

Array DYC1766-2

• VEGFR2/KDR/Flk-1 Antibodies
• VEGFR2/KDR/Flk-1 Antibody Pair
• VEGFR2/KDR/Flk-1 ELISA Kits
• VEGFR2/KDR/Flk-1 Proteins
• VEGFR2/KDR/Flk-1 ELISAs
• VEGFR2/KDR/Flk-1 Proteins and Enzymes