Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Human EMMPRIN/CD147 DuoSet ELISA, 15 Plate
5F7
basigin (Ok blood group)
Basigin
BSG
CD147 antigen
CD147
Collagenase stimulatory factor
EMMPRIN
EMMPRINTCSF
Extracellular matrix metalloproteinase inducer
Leukocyte activation antigen M6
M6
OK blood group antigen
OK
Tumor cell-derived collagenase stimulatory factor
Background
The name EMMPRIN reflects this proteins extracellular metalloproteinase inducer activity. It is a cell surface protein with two extracellular Ig domains, a transmembrane domain, and a cytoplasmic domain. Its expression is often elevated in human tumor cells, which in turn promotes MMP-1, MMP-2 and MMP-3 production in melanoma cells and MMP-2 and MMP-9 production in breast cancer cells. It interacts with several types of molecules such as integrins, caveolin-1 and MCT1. TRA-1-85 is an epitope within EMMPRIN.