Human E-Selectin/CD62E DuoSet ELISA, 15 Plate

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

The Selectin family is comprised of three members, E-Selectin, L-Selectin, and P-Selectin. E-Selectin [endothelial leukocyte adhesion molecule-1 (ELAM-1), CD62E] is transiently expressed on vascular endothelial cells in response to IL-1 beta and TNF-alpha. The human and rat proteins share approximately 67% amino acid sequence identity. The mouse and rat proteins share approximately 78% amino acid sequence identity. L-Selectin (Leukocyte Selectin, LAM-1, LECAM-1, LECCAM-1, TQ1, Leu-8, MEL-14 antigen, DREG, lymph node homing receptor, CD62L) is expressed constitutively on a wide variety of leukocytes. Two forms of L-Selectin have been reported, apparently arising as a result of post-translational modifications. Human and mouse L-Selectin share 76% amino acid sequence identity. Human P-Selectin (GMP-140, LECAM-3, PADGEM, CD62P) is expressed by activated platelets and endothelial cells. The extracellular domains of human and mouse P-Selectin share approximately 73% amino acid sequence identity.

We have publications tested in 1 confirmed species: Human.

Showing Publications 1 - 10 of 11. Show All 11 Publications. Collapse Publications.

Publications using DY724	Applications	Species
Hayderi, A;Zegeye, MM;Meydan, S;Sirsjö, A;Kumawat, AK;Ljungberg, LU; TNF Induces Laminin-332-Encoding Genes in Endothelial Cells and Laminin-332 Promotes an Atherogenic Endothelial Phenotype International journal of molecular sciences 2024-08-09 [PMID: 39201392] (Human)		Human
Li, JZ;Melberg, M;Kittilson, A;Abdel-Mohsen, M;Li, Y;Aga, E;Bosch, RJ;Wonderlich, ER;Kinslow, J;Giron, LB;Di Germanio, C;Pilkinton, M;MacLaren, L;Keefer, M;Fox, L;Barr, L;Acosta, E;Ananworanich, J;Coombs, R;Mellors, J;Deeks, S;Gandhi, RT;Busch, M;Landay, A;Macatangay, B;Smith, DM;AIDS Clinical Trials Group A5345 Study Team, ; Predictors of HIV rebound differ by timing of antiretroviral therapy initiation JCI insight 2024-02-08 [PMID: 38329130] (Human)		Human
S Asif, R Frithiof, A Larsson, S Franzén, SB Anderberg, B Kristensen, M Hultström, M Lipcsey Immuno-Modulatory Effects of Dexamethasone in Severe COVID-19-A Swedish Cohort Study Biomedicines, 2023-01-09;11(1):. 2023-01-09 [PMID: 36672672] (Human)		Human
N Kumar, Y Zuo, S Yalavarthi, KL Hunker, JS Knight, Y Kanthi, AT Obi, SK Ganesh SARS-CoV-2 Spike Protein S1-Mediated Endothelial Injury and Pro-Inflammatory State Is Amplified by Dihydrotestosterone and Prevented by Mineralocorticoid Antagonism Viruses, 2021-11-03;13(11):. 2021-11-03 [PMID: 34835015] (Human)		Human
V Chaban, ER Nakstad, H Stær-Jense, C Schjalm, I Seljeflot, J Vaage, C Lundqvist, JŠ Benth, K Sunde, TE Mollnes, GØ Andersen, SE Pischke Complement activation is associated with poor outcome after out-of-hospital cardiac arrest Resuscitation, 2021-06-11;0(0):. 2021-06-11 [PMID: 34126135] (Human)		Human
SP Pan, T Pirker, O Kunert, N Kretschmer, S Hummelbrun, SL Latkolik, J Rappai, VM Dirsch, V Bochkov, R Bauer C13 Megastigmane Derivatives From Epipremnum pinnatum: beta-Damascenone Inhibits the Expression of Pro-Inflammatory Cytokines and Leukocyte Adhesion Molecules as Well as NF-kappaB Signaling Front Pharmacol, 2019-11-28;10(0):1351. 2019-11-28 [PMID: 31849641] (Human)		Human
I Govorov, K Bremme, A Larsson, M Holmström, E Komlichenk, R Chaireti, M Mints Blood inflammatory and endothelial markers in women with von Willebrand disease PLoS ONE, 2019-01-10;14(1):e0210544. 2019-01-10 [PMID: 30629692] (Human)		Human
A Bokslag, C Franssen, LJ Alma, I Kovacevic, FV Kesteren, PW Teunissen, O Kamp, W Ganzevoort, PL Hordijk, CJM Groot, WJ Paulus Early-onset preeclampsia predisposes to preclinical diastolic left ventricular dysfunction in the fifth decade of life: An observational study PLoS ONE, 2018-06-12;13(6):e0198908. 2018-06-12 [PMID: 29894501] (Human)		Human
M Oleszowsky, MF Seidel Serum Soluble Vascular Cell Adhesion Molecule-1 Overexpression Is a Disease Marker in Patients with First-Time Diagnosed Antinuclear Antibodies: A Prospective, Observational Pilot Study Biomed Res Int, 2018-02-01;2018(0):8286067. 2018-02-01 [PMID: 29487871] (Human)		Human
M Du, A Martin, F Hays, J Johnson, RA Farjo, KM Farjo Serum retinol-binding protein-induced endothelial inflammation is mediated through the activation of toll-like receptor 4 Mol. Vis., 2017-03-31;23(0):185-197. 2017-03-31 [PMID: 28400700] (Human)		Human
Hsu HY, Wittemann S, Schneider EM, Weiss M, Joos TO Suspension microarrays for the identification of the response patterns in hyperinflammatory diseases. Med Eng Phys, 2008-03-03;30(8):976-83. 2008-03-03 [PMID: 18313970] (Human)		Human
Show All 11 Publications. Collapse Publications.

Array DY724

• E-Selectin/CD62E Antibodies
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• E-Selectin/CD62E Lysate
• E-Selectin/CD62E Proteins and Enzymes
• E-Selectin/CD62E ELISAs