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HO-1/HMOX1/HSP32 Antibody [mFluor Violet 450 SE]

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Product Details

Summary
Reactivity Hu, Mu, Pm-OrSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
mFluor Violet 450 SE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP1-77459AF350
Alexa Fluor 405
NBP1-77459AF405
Alexa Fluor 488
NBP1-77459AF488
Alexa Fluor 532
NBP1-77459AF532
Alexa Fluor 594
NBP1-77459AF594
Alexa Fluor 647
NBP1-77459AF647
Alexa Fluor 700
NBP1-77459AF700
Alexa Fluor 750
NBP1-77459AF750
Allophycocyanin
NBP1-77459APC
Biotin
NBP1-77459B
CoraFluor 1
NBP1-77459CL1
DyLight 350
NBP1-77459UV
DyLight 405
NBP1-77459V
DyLight 488
NBP1-77459G
DyLight 550
NBP1-77459R
DyLight 594
NBP1-77459DL594
DyLight 650
NBP1-77459C
DyLight 680
NBP1-77459FR
DyLight 755
NBP1-77459IR
FITC
NBP1-77459F
HRP
NBP1-77459H
Janelia Fluor 525
NBP1-77459JF525
Janelia Fluor 549
NBP1-77459JF549
Janelia Fluor 585
NBP1-77459JF585
Janelia Fluor 635
NBP1-77459JF635
Janelia Fluor 646
NBP1-77459JF646
Janelia Fluor 669
NBP1-77459JF669
PE
NBP1-77459PE
PerCP
NBP1-77459PCP
Unconjugated
NBP1-77459
mFluor Violet 500 SE
NBP1-77459MFV500
mFluor Violet 610 SE
NBP1-77459MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP1-77459
BSA Free
NBP1-77459SS
BSA Free
NBP1-77459
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HO-1/HMOX1/HSP32 Antibody [mFluor Violet 450 SE] Summary

Immunogen
A synthetic peptide made to an internal portion of the human Heme Oxygenase 1 protein (between residues 100-150) [UniProt# P09601]
Localization
Microsome. Endoplasmic reticulum.
Marker
Oxidative Stress Marker
Predicted Species
Orangutan (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
HMOX1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for HO-1/HMOX1/HSP32 Antibody [mFluor Violet 450 SE]

  • bK286B10
  • EC 1.14.99.3
  • heat shock protein, 32-kD
  • heme oxygenase (decycling) 1
  • HMOX1
  • HO
  • HO1
  • HO-1
  • HO-1heme oxygenase 1
  • HSP32

Background

Stressed mammalian cells up-regulate heme oxygenase 1 (HO-1), which catabolizes heme to biliverdin, carbon monoxide, and free iron. Results provide genetic evidence that up-regulation of HO-1 serves as an adaptive mechanism to protect cells from oxidative damage during stress (1). When cells are injured they release their contents, resulting in a local accumulation of free heme proteins and heme. HO-1 plays a crucial role in the inflammatory process during wound healing (2). TNFalpha accelerates inflammatory responses by down-regulating HO-1 expression in human monocytes. TNF antagonists may block this TNF-dependent suppression of HO-1 expression, resulting in an amelioration of inflammation (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HMOX1