Histone H1.1 Antibody Summary
Description |
Centrifuge briefly prior to opening. |
Immunogen |
Recombinant protein encompassing a sequence within the center region of human Histone H1.1. The exact sequence is proprietary. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
H1-1 |
Purity |
Antigen Affinity-purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Reactivity Notes
Packaging, Storage & Formulations
Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
Buffer |
PBS (pH 7), 20% Glycerol |
Preservative |
0.025% Proclin 300 |
Purity |
Antigen Affinity-purified |
Alternate Names for Histone H1.1 Antibody
Background
Histones are nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber as they play a critical role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. Histone H1.1 is a 215 amino acid long, 21 kDA protein encoded by the HIST1H1A gene. H1 proteins are essential in forming chromatin fiber and for the condensation of nucleosome chains into higher-order structured fibers. The HIST1H1A gene is active in apoptosis, PKA signaling, histone modification, and granzyme-A pathways. It interacts with genes CDK2, CDK7, CTCFL, DOT1L, and ADPRH. The HIST1H1A gene has been researched regarding measles, breast cancer, prostatitis, carcinoma, paratyphoid fever, and neuronitis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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