Acrosin Antibody

Acrosin is the major proteinase present in the acrosome of mature spermatozoa. It is a typical serine proteinase with trypsin-like specificity. It is stored in the acrosome in its precursor form, proacrosin. The active enzyme functions in the lysis of the zona pellucida, thus facilitating penetration of the sperm through the innermost glycoprotein layers of the ovum. The mRNA for proacrosin is synthesized only in the postmeiotic stages of spermatogenesis. In humans proacrosin first appears in the haploid spermatids.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 4 applications: ICC/IF, IF/IHC, Immunocytochemistry/ Immunofluorescence, WB.

Showing Publications 1 - 10 of 12. Show All 12 Publications. Collapse Publications.

Publications using NBP2-14260	Applications	Species
Hua R, Xue R, Liu Y et al. ACROSIN deficiency causes total fertilization failure in humans by preventing the sperm from penetrating the zona pellucida Human reproduction (Oxford, England) 2023-06-01 [PMID: 37004249]
Yu H, Shi X, Shao Z et al. Novel HYDIN variants associated with male infertility in two Chinese families Frontiers in endocrinology 2023-01-18 [PMID: 36742411] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Ma Y, Chen J, Li H et al. Immature rat testis sustained long-term development using an integrative model Biological research 2022-10-04 [PMID: 36195947] (IF/IHC, Rat)	IF/IHC	Rat
Tian-Ying Yang, Ying Chen, Guo-Wu Chen, Yi-Si Sun, Zhi-Chao Li, Xiao-Rong Shen, Yi-Ni Zhang, Wen He, Dan Zhou, Hui-Juan Shi, Ai-Jie Xin, Xiao-Xi Sun Sperm-specific protein ACTL7A as a biomarker for fertilization outcomes of assisted reproductive technology Asian Journal of Andrology 2022-01-01 [PMID: 35532568]
Yang TY, Chen Y, Chen GW et al. Sperm-specific protein ACTL7A as a biomarker for fertilization outcomes of assisted reproductive technology Asian journal of andrology 2022-02-18 [PMID: 35229759] (WB, Human)	WB	Human
Zhao Q, Huang JF, Cheng Y Et al. Polyamine metabolism links gut microbiota and testicular dysfunction Microbiome 2021-11-11 [PMID: 34758869] (IF/IHC, Mouse)	IF/IHC	Mouse
Sawaied A, Arazi E, AbuElhija A et al. The Presence of Colony-Stimulating Factor-1 and Its Receptor in Different Cells of the Testis; It Involved in the Development of Spermatogenesis In Vitro International Journal of Molecular Sciences 2021-02-26 [PMID: 33652607] (Immunocytochemistry/ Immunofluorescence)	Immunocytochemistry/ Immunofluorescence
Nakamura N, Sloper DT Comparison of germ cell differentiation of rat testis fragments cultured in knockout serum replacement versus Albumax I Birth defects research 2020-12-21 [PMID: 33348473]
Sawaied A, Lunenfeld E, Huleihel M. Interleukin-34, a Novel Paracrine/Autocrine Factor in Mouse Testis, and Its Possible Role in the Development of Spermatogonial Cells In Vitro International Journal of Molecular Sciences 2020-10-30 [PMID: 33143373]
Xin A, Qu R, Chen G et al. Disruption in ACTL7A causes acrosomal ultrastructural defects in human and mouse sperm as a novel male factor inducing early embryonic arrest Sci. Adv. 2020-08-01 [PMID: 32923619] (ICC/IF, Human, Mouse)	ICC/IF	Human, Mouse
Nakamura N, Merry GE, Inselman AL et al. Evaluation of Culture Time and Media in an In Vitro Testis Organ Culture System. Birth Defects Res. 2017-04-17 [PMID: 28398669]
Reda A, Hou M, Winton TR et al. In vitro differentiation of rat spermatogonia into round spermatids in tissue culture. Mol. Hum. Reprod. 2016-07-18 [PMID: 27430551] (IF/IHC, ICC/IF, Rat)	IF/IHC, ICC/IF	Rat
Show All 12 Publications. Collapse Publications.

Array NBP2-14260

• Acrosin Antibodies
• Acrosin ELISA Kits
• Acrosin Protein