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H4/n Antibody (7A2E10) - BSA Free

Images

 
Flow Cytometry: H4/n Antibody (7A2E10) [NBP2-52489] - Analysis of Raji cells using HIST2H4A(20Me3) mouse mAb (green) and negative control (red).
ELISA: H4/n Antibody (7A2E10) [NBP2-52489] - Black line: Control Antigen (100 ng); Purple line: Antigen(10ng); Blue line: Antigen (50 ng); Red line: Antigen (100 ng).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA, Flow, CyTOF-ready
Clone
7A2E10
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

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H4/n Antibody (7A2E10) - BSA Free Summary

Immunogen
Synthesized peptide of human H4/n (AA: GGAKRHRK(Me3)VLRDNIQ) .
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
HIST2H4A
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • ELISA 1:10000
  • Flow Cytometry 1:200-1:400
Application Notes
This antibody is Cytof ready.
Theoretical MW
11.4 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Protein G purified

Alternate Names for H4/n Antibody (7A2E10) - BSA Free

  • FO108
  • H4 histone family, member N
  • H4 histone, family 2
  • H4
  • H4/A
  • H4/D
  • H4/E
  • H4/G
  • H4/H
  • H4/I
  • H4/J
  • H4/K
  • H4/M
  • H4/n
  • H4/O
  • H4F2H4/B
  • H4FA
  • H4FB
  • H4FC
  • H4FD
  • H4FE
  • H4FG
  • H4FH
  • H4FI
  • H4FJ
  • H4FK
  • H4FM
  • H4FNH4/C
  • H4FO
  • HIST1H4A
  • HIST1H4B
  • HIST1H4C
  • HIST1H4D
  • HIST1H4E
  • HIST1H4F
  • HIST1H4H
  • HIST1H4I
  • HIST1H4J
  • HIST1H4K
  • HIST1H4L
  • HIST2H4
  • HIST2H4B
  • HIST4H4
  • histone 2, H4
  • histone 2, H4a
  • histone cluster 2, H4a
  • histone H4
  • histone IV, family 2

Background

Histones are nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber as they play a critical role in transcription regulation, DNA repair, DNA replication, and chromosomal stability. H4/N is a103 amino acid long, 11 kDA protein encoded by the HIST2H4A gene found on chromosome 1. HIST2H4A is one of four histone genes in this specific cluster that are duplicated, representing the centromeric copy. HIST2H4A is involved in type II interferon signaling, development notch signaling pathway, transcription Sin3 and NuRD in transcription regulation, and telomere maintenance through interactions with genes HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, and HIST1H3F. It has been investigated for its role in lymphoma, carcinoma, leukemia, herpes simplex, thyroiditis, and lupus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol HIST2H4A